96962-33-3

Upstream product

• 124-42-5 acetamidine hydrochloride 
• 5292-53-5 diethyl benzalmalonate 
• 100-52-7 benzaldehyde 

Downstream Products

• 1337541-32-8 1-tert-butyl 5-ethyl 2-methyl-6-phenyl-4-o-tolyl-1,6-dihydropyrimidine-1,5-dicarboxylate 
• 1337541-33-9 1-tert-butyl 5-ethyl 4-p-methoxyphenyl-2-methyl-6-phenyl-1,6-dihydropyrimidine-1,5-dicarboxylate 
• 1337541-34-0 1-tert-butyl 5-ethyl 2-methyl-4-p-nitrophenyl-6-phenyl-1,6-dihydropyrimidine-1,5-dicarboxylate 
• 1337541-35-1 1-tert-butyl 5-ethyl 2-methyl-6-phenyl-4-trans-styryl-1,6-dihydropyrimidine-1,5-dicarboxylate 
• 1337541-36-2 1-tert-butyl 5-ethyl 4-ethyl-2-methyl-6-phenyl-1,6-dihydropyrimidine-1,5-dicarboxylate 
• 1337541-37-3 1-tert-butyl 5-ethyl 2-methyl-6-phenyl-4-(thiophen-3-yl)-1,6-dihydropyrimidine-1,5-dicarboxylate 
• 1337541-38-4 5-ethyl 2-methyl-4,6-diphenyl-1,6-dihydropyrimidine-1,5-dicarboxylate 
• 1337541-39-5 5-ethyl 2-methyl-6-(2-methyl)phenyl-4-phenyl-1,4-dihydropyrimidine-1,5-dicarboxylate 
• 1337541-40-8 5-ethyl 2-methyl-4-(4-methoxy)phenyl-6-phenyl-1,6-dihydropyrimidine-1,5-dicarboxylate 
• 1337541-41-9 5-ethyl 2-methyl-4-(4-nitro)phenyl-6-phenyl-1,6-dihydropyrimidine-1,5-dicarboxylate 
• 1337541-42-0 5-ethyl 2-methyl-4-trans-styryl-6-phenyl-1,6-dihydropyrimidine-1,5-dicarboxylate 
• 1337541-43-1 5-ethyl 4-ethyl-2-methyl-6-phenyl-1,6-dihydropyrimidine-1,5-dicarboxylate 
• 1337541-44-2 5-ethyl 2-methyl-6-phenyl-4-(thiophen-3-yl)-1,6-dihydropyrimidine-1,5-dicarboxylate 
• 1337541-30-6 1-tert-butyl 5-ethyl 4-chloro-2-methyl-6-phenyl-1,6-dihydropyrimidine-1,5-dicarboxylate 

Relevant academic research and scientific papers

Synthesis and substitution reactions of 4(6)-chlorodihydropyrimidines

Chlorination of the corresponding ketones with phenylphosphonic dichloride (PhPOCl2) provided ethyl 6(4)-chloro-2-methyl-4(6)-phenyl-1,4(6)- dihydropyrimidine-5-carboxylate in good yield. The cross-coupling reactions of organoboronic acids or t

SYNTHESIS OF NOVEL 5-ALKOXYCARBONYL-5,6-DIHYDROPYRIMIDIN-4(3H)-ONES FROM 3-SUBSTITUTED 2-ALKOXYCARBONYL-2-PROPENOATES AND AMIDINES

A cyclization of 3-substituted 2-alkoxycarbonyl-2-propenoates with acetamidine, benzamidine, guanidine, or 1,1-dimethylguanidine hydrochloride in the presence of 1-2 eq of metal alkoxide afforded novel 5-alkoxycarbonyl-5,6-dihydropyrimidin-4(3H)-ones in g