97188-19-7Relevant academic research and scientific papers
Unusual photorearrangement of 1,7-disubstituted 7-azabenzonorbornadiene
Altundas,Tepe,Akbulut,Kara
, p. 613 - 616 (2009)
1-(11-Benzoyl-11-azatricyclo[6.2.1.02,7]undeca-2,4,6,9-tetraen- 1-yl)ethanone was synthesized by cycloaddition of 2-acetyl-N-benzoylpyrrole to benzyne. Direct photolysis of 1-(11-benzoyl-11-azatricyclo-[6.2.1.0 2,7]undeca-2,4,6,9-tet
Pyrrole chemistry. XXVIII. Substitution reactions of 1-(phenylsulfonyl)pyrrole and some derivatives
Anderson, Hugh J.,Loader, Charles E.,Xu, Ru Xun,Le, Nghia,Gogan, Niall J.,et al.
, p. 896 - 902 (2007/10/02)
The preparative value of the 1-(phenylsulfonyl) N-blocking and directing group for the synthesis of 3-acylpyrroles has been further evaluated.Acetylation and benzoylation are strongly regiospecific and give good yields.However, the regiospecificity is not general and other substitution reactions give mixtures of 2- and 3-substitution or even mostly 2-substitution.Friedel and Crafts tert-butylation gives 3-tert-butyl-1-(phenylsulfonyl)pyrrole and provides a useful route to tert-butylpyrrole, but ethylation and isopropylation give mixtures.Acylations of 2- and 3-alkyl-1-(phenylsulfonyl)pyrroles show little evidence of useful regiospecificity.
