97300-81-7Relevant academic research and scientific papers
Acid mediated decarboxylation of glycidic acids: Normal and rearranged products
Bansal, R K,Sharma, V K
, p. 482 - 485 (2007/10/02)
Two α-substituted t-butyl phenylglycidic esters have been synthesized by the familiar Darzens condensation.Acid-catalysed decarboxylation of the glycidic acids afford a mixture of two carbonyl compounds in each case.The analysis of the reaction mixture has been accomplished by HPLC and the structure of the products have been confirmed by synthesis.The previously reported mechanism does not seem to fully explain the formation of all the products.We believe that the formation of an aldehyde or ketone is function of the stability of the carbocation formed at the α- or β-position.
A Novel Reaction Type Promoted by Aqueous Titanium Trichloride. Synthesis of Unsymmetrical 1,2-Diols
Clerici, Angelo,Porta, Ombretta
, p. 2852 - 2856 (2007/10/02)
Electron-withdrawing substituted carbonyl compounds when allowed to react with 2 equiv of aqueous titanium trichloride in the presence of acetone, acetaldehyde, or benzaldehyde afford unsymmetrical 1,2-diols in high yields under very simple experimental conditions.
