1273546-88-5

Basic information

• Product Name: tert-butyl 2-bromo-4-methoxyphenethylcarbamate
• Synonyms: tert-butyl 2-bromo-4-methoxyphenethylcarbamate
• CAS NO: 1273546-88-5
• Molecular Weight: 330.222
• Mol File: 1273546-88-5.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl 2-bromo-4-methoxyphenethylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-bromo-4-methoxyphenethylcarbamate(1273546-88-5)
• EPA Substance Registry System: tert-butyl 2-bromo-4-methoxyphenethylcarbamate(1273546-88-5)

Safety Data

• Hazardous Substances Data: 1273546-88-5(Hazardous Substances Data)

Upstream product

• 158690-56-3 2-(tert-butoxycarbonylamino)ethyl-4-methylbenzenesulfonate 
• 466639-53-2 3-bromo-4-iodoanisole 
• 97308-23-1 N-(tert-butoxycarbonyl)aziridine 
• 1037298-05-7 3-bromo-4-iodophenol 
• 1428963-74-9 3-bromo-4-iodophenyl methanesulfonate 
• 191719-02-5 4-amino-3-bromophenyl methanesulfonate 
• 24690-19-5 methanesulfonic acid 4-aminophenyl ester 
• 20455-07-6 p-nitrophenyl methanesulfonate 
• 100-02-7 4-nitro-phenol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 66916-98-1 2-(2-bromo-4-methoxyphenyl)acetonitrile 

Downstream Products

• 1394248-15-7 tert-butyl 6-methoxyindoline-1-carboxylate 
• 1428963-59-0 tert-butyl 6-methoxy-7-(4-methoxyphenyl)indoline-1-carboxylate 
• 1428963-60-3 tert-butyl 6-methoxy-7-(4-(trifluoromethyl)phenyl)indoline-1-carboxylate 
• 1428963-61-4 tert-butyl 7-(4-bromophenyl)-6-methoxyindoline-1-carboxylate 
• 1428963-46-5 tert-butyl 7-deuterio-6-methoxyindoline-1-carboxylate 
• 1428963-66-9 tert-butyl 2-methoxy-1-(4-methoxyphenyl)-9H-carbazole-9-carboxylate 
• 113521-05-4 2-(2-bromo-4-methoxyphenyl)ethanamine 
• 1428963-75-0 N-benzyl-2-(2-bromo-4-methoxyphenyl)ethanamine 
• 1428963-76-1 C₂₄H₃₄BrNO₃S 
• 1428963-48-7 C₂₄H₃₂BrNO₃S 
• 1428963-63-6 tert-butyl 6-methoxy-7-(phenylethynyl)indoline-1-carboxylate 
• 1273547-01-5 (3S)-(E)-N-Boc-N-[2-[2-[3-(tert-butyldimethylsilyloxy)-but-1-enyl]-4-methoxyphenyl]ethyl]amine 
• 1273547-10-6 (3S)-(E)-N-Boc-N-[2-[2-[3-hydroxybut-1-enyl]-4-methoxyphenyl]ethyl]amine 

Relevant articles and documents

Synthesis of substituted indoline and carbazole by benzyne-mediated cyclization-functionalization

A benzyne-mediated synthesis of substituted indolines and carbazoles was developed. The reaction includes generation of benzyne using Mg(TMP) 2·2LiCl as a base, cyclization, and trapping the resulting organomagnesium intermediate with an electr

Synthesis of chiral 1-substituted tetrahydroisoquinolines by the intramolecular 1,3-chirality transfer reaction catalyzed by Bi(OTf)3

The intramolecular 1,3-chirality transfer reaction of chiral amino alcohols 1 with 99% ee was developed to construct chiral 1-substituted tetrahydroisoquinoline 2. Bi(OTf)3 (10 mol %)-catalyzed cyclization of 1 (R = H) afforded (S)-1-(E)-propenyl tetrahydroisoquinoline 2 (R = H) in 83% yield with a ratio of 98:2. The stereochemistry at the newly formed chiral center was produced by a syn SN2′-type process. In this reaction, the substituent on the benzene ring of 1 significantly affected the reactivities and selectivities. A plausible reaction mechanism was proposed.