97356-11-1Relevant academic research and scientific papers
Desymmetrization of meso-glycerol derivatives induced by L -histidine-derived acylation catalysts
Sakakura, Akira,Umemura, Shuhei,Ishihara, Kazuaki
supporting information; experimental part, p. 1938 - 1942 (2011/10/08)
The desymmetrization of meso-glycerol derivatives bearing a 3-pyrroline-1-carbonyl (Pyroc) directing group is demonstrated through an enantioselective acylation reaction promoted by L-histidine-derived bifunctional catalysts. The desired monoacylated products are obtained in good yields (up to 74%) with high enantioselectivities (up to 99% ee). Copyright
