97514-97-1

Basic information

• Product Name: TRANS-5-TRIMETHYLSILYL-2-PENTEN-4-YN-1-OL
• Synonyms: TRANS-5-TRIMETHYLSILYL-2-PENTEN-4-YN-1-OL;(E)-5-TRIMETHYLSILYL-2-PENTEN-4-YN-1-OL;5-(TRIMETHYLSILYL)PENT-2-EN-4-YN-1-OL
• CAS NO: 97514-97-1
• Molecular Formula: C₈H₁₄OSi
• Molecular Weight: 154.28166
• Mol File: 97514-97-1.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: TRANS-5-TRIMETHYLSILYL-2-PENTEN-4-YN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: TRANS-5-TRIMETHYLSILYL-2-PENTEN-4-YN-1-OL(97514-97-1)
• EPA Substance Registry System: TRANS-5-TRIMETHYLSILYL-2-PENTEN-4-YN-1-OL(97514-97-1)

Safety Data

• Hazardous Substances Data: 97514-97-1(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 5557-88-0 pent-2-en-4-yn-1-ol 
• 56053-89-5 5-trimethylsilanyl-penta-2,4-diyn-1-ol 
• 18163-47-8 iodoethynyltrimethylsilane 
• 16205-84-8 ethyl 3-(trimethylsilyl)propynoate 
• 109384-43-2 (E)-5-trimethylsilanylpent-2-en-4-ynoic acid methyl ester 
• 1066-54-2 trimethylsilylacetylene 
• 54599-61-0 ethyl (2E)-5-trimethylsilyl-pent-2-en-4-ynoate 
• 37428-50-5 (2E)-3-iodo-2-propen-1-ol 
• 35042-52-5 (E)-2-penten-4-yn-1-ol 

Downstream Products

• 97514-88-0 [2(E)-5-(trimethylsilyl)pent-2-en-4-ynyl]triphenylphosphonium bromide 
• 959410-03-8 (E)-5-(trimethylsilyl)pent-2-en-4-ynyl (toluene-4-sulfonyl)acetate 
• 130288-22-1 (R,4Z,6Z,8E)-3-hydroxy-2,2,4-trimethyl-10-(oxazol-5-yl)deca-4,6,8-trienamide 
• 95341-55-2 (7E,9E,11E,13E)-(5R,6S,15S)-5,6,15-Trihydroxy-icosa-7,9,11,13-tetraenoic acid 
• 94292-82-7 (7E,9E,11Z,13E)-(5R,6S,15S)-5,6,15-Trihydroxy-icosa-7,9,11,13-tetraenoic acid 
• 94292-84-9 (7E,9E,11E,13E)-(5S,6S,15S)-5,6,15-Trihydroxy-icosa-7,9,11,13-tetraenoic acid 
• 94292-80-5 6S-Lipoxin A₄ 
• 17098-68-9 (2E,8E)2,8-decadien-4,6-diyn-1-ol 
• 1002-64-8 (2E,8E)-1-acetoxy-2,8-decadien-4,6-diyne 

Relevant articles and documents

Cobalt-Catalyzed Diastereo- And Enantioselective Reductive Allyl Additions to Aldehydes with Allylic Alcohol Derivatives via Allyl Radical Intermediates

Catalytic generation of ambiphilic π-allyl-metal complexes and their utility in enantioselective transformations constitutes a powerful approach for introduction of allyl groups to a molecule. Herein an unprecedented cobalt-catalyzed highly site-, diastereo-, and enantioselective protocol for stereoselective formation of nucleophilic allyl-Co(II) complexes followed by addition to aldehydes is presented. The reaction features diastereo- and enantioconvergent conversion of easily accessible allylic alcohol derivatives to diversified enantioenriched homoallylic alcohols with a remarkably broad scope of allyl groups that can be introduced. Mechanistic studies indicated that allyl radical intermediates were involved in this process. These new discoveries establish a new strategy for development of enantioselective transformations through capture of radicals by chiral Co complexes, pushing forward the frontier of Co complexes for enantioselective catalysis.

Synthesis of hydroxylated pyrrolidines by allenic cyclisation

The diastereoselective gold(I) catalysed cyclisation of highly substituted aminoallene derivatives allows the synthesis of both epi-DAB-1 and di-epi-lentiginosine. While the sense of stereoselectivity observed is in line with earlier observations on analo

A convergent approach to (-)-callystatin a based on local symmetry

The key is symmetry! A convergent synthetic approach of the highly cytotoxic natural product (-)-callystatin A was developed assembling three fragments through Julia-Kocienski olefination and Stille cross-coupling. The new strategy relies on a pivotal local symmetry of the target molecule. In this preliminary study, particular attention was devoted to facilitate the catalytic enantiocontrol of strategic stereogenic centers present in each of the fragments (see scheme). Copyright