97684-12-3

Upstream product

• 109-80-8 1.3-propanedithiol 
• 20442-65-3 1-(4-methylphenyl)-3-phenylprop-2-yn-1-one 
• 54731-27-0 1-p-methylphenyl-1-trimethylsiloxyethene 

Downstream Products

• 25855-99-6 1-(4-methylphenyl)-3-phenyl-1,3-propanedione 

Relevant academic research and scientific papers

Double Michael addition of dithiols to acetylenic carbonyl compounds under the influence of molecular sieve and dimethyl sulfoxide

Double Michael addition of dithiols such as 1,3-propanedithiol and 1,2-ethanedithiol to α,β-acetylenic carbonyl compounds in the presence of molecular sieve and dimethyl sulfoxide proceeds very smoothly to afford the corresponding β-keto 1,3-dithianes and

1,3-Dithienium- and 1,3-Dithiolenium Salts, II. Synthesis of Monocyclothioacetalized 1,3-Diketones from Silyl Enol Ethers

The 1,3-dithienium and 1,3-dithiolenium salts 3, available from the dithiols 1 or the cyclic thioacetals 4 (n=2, 3) by reaction with the acyl chlorides 2, trityl tetrafluoroborate (5), and sulfuryl chloride (7), react in good yields with the silyl enol ethers 10 to give the new monocyclothioacetalized 1,3-diketones 11.The synthetic potential of 11 as partially protected 1,3-diketones is demonstrated exemplarily by dethioacetalization to the 1,3-dicarbonyl compounds 13.