97861-42-2

Upstream product

• 108-24-7 acetic anhydride 
• 3261-90-3 2-(4-methoxyphenyl)-4-oxo-4-phenylbutanoic acid 
• 75-36-5 acetyl chloride 
• 72036-37-4 ethyl 4-hydroxy-4-phenylbut-2-ynoate 
• 5720-07-0 4-methoxyphenylboronic acid 
• 768-60-5 4-methoxyphenylacetylen 

Downstream Products

• 110851-39-3 4,4'-bis-(4-methoxy-phenyl)-2,2'-diphenyl-2H,2'H-[2,2']bifuryl-5,5'-dione 
• 97861-54-6 C₁₇H₁₃O₃ 
• 97861-40-0 3-benzyl-3-(4-methoxyphenyl)-5-phenyl-2(3H)-furanone 

Relevant academic research and scientific papers

Regioselective Pd-catalyzed alkylative lactonizations of 4-hydroxy-2-alkynecarboxylates with organoboronic acids

The Pd-catalyzed addition of organoboronic acids to 4-hydroxy-2- alkynecarboxylates and in situ lactonization gave the butenolides with a high control of regioselectivity.

Highly regioselective Lewis acid-catalyzed [3+2] cycloaddition of alkynes with donor-acceptor oxiranes by selective carbon-carbon bond cleavage of epoxides

A novel, efficient, highly regioselective Sc(OTf)3-catalyzed [3+2] cycloaddition of electron-rich alkynes with donor-acceptor oxiranes via highly chemoselective C-C bond cleavage under mild conditions was developed.

Conversion of 3-aryl-5-phenyl-2(3H)-furanones into 3(2H)-isothiazolone derivatives

Upon heating 3-aryl-5-phenyl-2(3H)-furanones (1a-C) with benzylamine at 100°C in the absence of solvents, ring opening occurred with the formation of the corresponding N-benzylamides (3a-c). When the latter compounds (3a-c) were allowed to react with thionyl chloride at room temperature, lhe corresponding isothiazolones (4a-c) were obtained. Treatment of the isothiazolones (4a-c) with sodium hydroxide in benzene at room temperature affected debenzoylation to give the corresponding 2-benzyl-4-aryl-3(2H)-isothiazolones (5a-c).