97892-66-5 Usage
General Description
7-Chloro-4-hydrazino-2-methylquinoline is a chemical compound with the molecular formula C11H10ClN3. It is a derivative of quinoline and contains a chlorine atom, a hydrazino group, and a methyl group. 7-CHLORO-4-HYDRAZINO-2-METHYLQUINOLINE is used in pharmaceutical research and development due to its potential biological activities. It has been studied for its antimicrobial, antitumor, and antiviral properties, and may have potential applications in the treatment of various diseases. Additionally, 7-chloro-4-hydrazino-2-methylquinoline is also a versatile building block for the synthesis of other organic compounds. However, it is important to handle this chemical with proper care and understanding of its potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 97892-66-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,8,9 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 97892-66:
(7*9)+(6*7)+(5*8)+(4*9)+(3*2)+(2*6)+(1*6)=205
205 % 10 = 5
So 97892-66-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H10ClN3/c1-6-4-10(14-12)8-3-2-7(11)5-9(8)13-6/h2-5H,12H2,1H3,(H,13,14)
97892-66-5Relevant articles and documents
N1-{4-[(10S)-Dihydroartemisinin-10-oxyl]}phenylmethylene-N 2-(2-methylquinoline-4-yl)hydrazine derivatives as antiplasmodial falcipain-2 inhibitors
Luo, Wei,Liu, Yang,Wang, Jian,Guo, Chun,Lu, Wei-Qiang,Cui, Kun-Qiang
, p. 3073 - 3079,7 (2020/08/20)
A series of N1-{4-[(10S)-dihydroartemisinin- 10-oxyl]}phenylmethylene-N2-(2-methylquinoline-4-yl) hydrazine derivatives 9a-9n possessing 4-quinolylhydrazone and artemisinin cores were herein synthesized and evaluated for their activities against cysteine protease falcipain- 2 of Plasmodium falciparum. The structures were clearly confirmed by elemental analysis, 1H NMR, and mass spectra. The pharmacological results indicated that all compounds showed excellent activity against recombinant falcipain-2 (IC50 = 0.15-2.28 μM). The best one of this series was compound 9d (IC50 = 0.15 μM). The molecular docking results showed that the compound 9d made close contact with the key active site of cysteine protease falcipain-2.
Quinolylhydrazones with potential antimicrobial and antiparasitic activity
Pellerano,Savini,Brizzi
, p. 486 - 492 (2007/10/02)
-