98-34-0Relevant articles and documents
Method for achieving pipe-type continuous production of CLT acid nitride
-
, (2016/11/17)
The invention discloses a method for achieving pipe-type continuous production of CLT acid nitride. The method comprises the steps that 1, methylbenzene and sulfuric acid conduct a sulfonation reaction in a sulfonation pipe reactor; 2, thth sulfonation reaction solution obtained in the first step and chlorine are continuously fed into a chlorination pipe reactor for a chlorination reaction; 3, the chlorination reaction solution obtained in the second step and nitric acid are continuously fed into a nitrification pipe reactor for a nitrification reaction, and then the CLT acid nitride is prepared. According to the method for achieving pipe-type continuous production of the CLT acid nitride, purification treatment does not need to be conducted on an intermediate in the reaction process, operation is easy, the reaction efficiency is high, and the objective product selectivity is high.
Highly selective oxidative monochlorination to synthesize organic intermediates: 2-Chlorotoluene, 2-chloroaniline, 2-chlorophenol, and 2-chloro-4-methylphenol
Mukhopadhyay, Sudip,Chandnani, Kavita H.,Chandalia, Sampatraj B.
, p. 196 - 200 (2013/09/08)
An alternative manufacturing process scheme was developed to synthesize monochloro-substituted aromatic compounds in high selectivity, involving oxidalive chlorination by using HCI-H2O2. Thus, 2-chlorotoluene, 2-chloroaniline, and 2-chlorophenol were synthesized by oxidative chlorination followed by desulphonation or decarboxylation. Oxidative chlorination of 4-methylbenzenesulphonic acid, 4-methylbenzoic acid, 4-aminobenzoic acid, and 4-hydroxybenzoic acid by using a suitable ratio of reactantr:HCI:H2O2, and their subsequent desulphonation or decarboxylation, gave 60-85% yield of the desired products. Oxidative chlorination of 4-methylphenol by using HCI-H2O2 gave as high as 98% selectivity to the desired 2-chloro-4-methylphenol.