98013-04-8

Upstream product

• 31558-03-9 1-(3-oxo-3-phenyl-propyl)-pyrrolidin-2-one 
• 936-59-4 3-chloropropiophenone 
• 886-06-6 1-phenyl-3-piperidino-propan-1-one; hydrochloride 
• 3506-36-3 3-dimethylaminopropiophenone 
• 768-03-6 Phenyl vinyl ketone 
• 75-20-7 calcium carbide 
• 100-52-7 benzaldehyde 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 

Downstream Products

• 25871-69-6 1,3,5-tribenzoylbenzene 

Relevant academic research and scientific papers

One-step construction of saturated six-membered rings directly using calcium carbide as an acetylene source: synthesis of 1,3,5-triaroylcyclohexanes

Saturated six-membered rings were constructed directly using calcium carbide as an acetylene source by one-step procedure, and functionalized cyclohexanes, 1,3,5-triaroylcyclohexanes, were efficiently synthesized by reactions of calcium carbide with aroma

The mechanism of cyclotrimerisation of phenylvinylketones and the crystal structures of 1-((1R*,2S*,3R*,5S*)- and 1-((1R*,2S*,3R*,5R*)-3,5-dibenzoyl-2-hydroxy-2- phenylcyclohexylmethyl)-pyrrolidin-2-on

The cyclotrimerisation of 1-phenyl-2-propyn-1-ol (1) with pyrrolidin-2-one (2) to the tribenzoylcyclohexanes 4 and 5 produced - with modifications of the reaction conditions - the phenylvinylketone adducts 17 and 18 as intermediates and additionally the c

Trisubstituted Cyclohexanes

C-Tertiary vinylketones or the corresponding masked vinylketone derivatives react with pyrrolidin-2-one in the system sodium hydride/dimethylsulfoxide to substituted cyclohexanes of the 1,3,5- and sometimes additionally of the 1,2,4-type.Only acetophenone Mannich bases bearing a p-hydroxy or a dimethylamino group failed in cyclization. - Key words: Cyclotrimerisation, Vinylketones, Mannich Bases, NMR Spectra