98018-50-9Relevant academic research and scientific papers
Hydrogen peroxide triggered prochelator activation, subsequent metal chelation, and attenuation of the fenton reaction
Wei, Yibin,Guo, Maolin
, p. 4722 - 4725 (2007)
(Chemical Equation Presented) Fenton antidote: The prochelator 2-boronobenzaldehyde isonicotinoyl hydrazone (SIH-B) reacts with H 2O2 to yield the active chelator salicylaldehyde isonicotinoyl hydrazone (SIH), which sequesters copper
Modifications of boronic ester pro-chelators triggered by hydrogen peroxide tune reactivity to inhibit metal-promoted oxidative stress
Charkoudian, Louise K.,Pham, David M.,Kwon, Ashley M.,Vangeloff, Abbey D.,Franz, Katherine J.
, p. 5031 - 5042 (2008/03/13)
Several new analogs of salicylaldehyde isonicotinoyl hydrazone (SIH) and salicylaldehyde benzoyl hydrazone (SBH) that contain an aryl boronic ester (BSIH, BSBH) or acid (BASIH) in place of an aryl hydroxide have been synthesized and characterized as maske
