98021-62-6Relevant articles and documents
Haloacetylated Enol Ethers. 8 [12]. Reaction of β-Alkoxyvinyl Trihalomethyl Ketones with Guanidine Hydrochloride. Synthesis of 4-Trihalomethyl-2-Aminopyrimidines
Zanatta, Nilo,Cortelini, Maria De F. M.,Carpes, Marcos J. S.,Bonacorso, Helio G.,Martins, Marcos A. P.
, p. 509 - 513 (2007/10/03)
In this work the results of the reaction of β-alkoxyvinyl trihalomethyl ketones 1, 2a-e, with guanidine hydrochloride are reported. Depending on the ketone 1 or 2 and the conditions under which the reactions were carried out, 4-trihalomethyl-2-amino pyrimidines, β-alkoxyvinyl carboxylic acids, or β-acetal carboxylic esters were obtained.