98166-23-5

Basic information

• Product Name: 2H-Pyran-3(6H)-one
• Synonyms: 2H-Pyran-3(6H)-one
• CAS NO: 98166-23-5
• Molecular Formula: C₅H₆O₂
• Molecular Weight: 98.09994
• Mol File: 98166-23-5.mol

Chemical Properties

• Boiling Point: 51-53 °C(Press: 3-4 Torr)
• Appearance: /
• Density: 1.123±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2H-Pyran-3(6H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran-3(6H)-one(98166-23-5)
• EPA Substance Registry System: 2H-Pyran-3(6H)-one(98166-23-5)

Safety Data

• Hazardous Substances Data: 98166-23-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2H-Pyran-3(6H)-one is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs. Its unique structure allows for the creation of molecules with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2H-Pyran-3(6H)-one serves as a precursor for the preparation of agrochemicals, aiding in the development of compounds that can be used in pest control and crop protection.
Used in Organic Synthesis:
2H-Pyran-3(6H)-one is utilized as a building block in organic synthesis for the construction of complex organic molecules, thanks to its reactivity and structural features that facilitate the formation of diverse chemical entities.
Used in Research and Development:
2H-Pyran-3(6H)-one is also used in research and development settings to explore its potential applications and to understand its chemical behavior, which can lead to innovations in drug discovery and the synthesis of novel organic compounds.

Upstream product

• 98166-29-1 2-(3-Propinyloxy)-acetaldehyddiethylacetal 
• 445378-38-1 3,6-dihydro-2H-pyran-3-ol 
• 329684-87-9 (±)-6-[(tert-butyldimethylsilyl)oxy]-3,6-dihydro-2H-pyran-3-one 
• 35436-57-8 6-hydroxy-3,6-dihydro-2H-pyran-3-one 
• 98-00-0 (2-furyl)methyl alcohol 
• 78735-39-4 1-(allyloxy)butyl-3-ene-2-ol 
• 497063-16-8 1-(prop-2-en-1-yloxy)but-3-en-2-one 

Downstream Products

• 23462-75-1 5,6-dihydro-2H-pyran-3(4H)-one 
• 1403864-09-4 benzyl N-(5-hydroxyoxan-3-yl)carbamate 
• 1403864-10-7 5-amino-tetrahydro-2H-pyran-3-ol 
• 884306-77-8 (5-oxo-tetrahydro-pyran-3-yl)-carbamic acid benzyl ester 
• 98166-36-0 5,10-Diphenyl-2H-naphtho<2,3-c>pyran-4-(3H)-on 

Relevant articles and documents

THERAPEUTIC COMPOUNDS

Compounds of formula (I) or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and thera

SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

Provided herein are Diaminopyrimidine Compounds having the following structures: wherein R1, R2, R3, and R4 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidine Compound, and methods for treating or preventing liver fibrotic disorders or a condition treatable or preventable by inhibition of a JNK pathway.

Synthesis of 3-oxooxa- and 3-oxoazacycloalk-4-enes by ring-closing metathesis. Application to the synthesis of an inhibitor of cathepsin K

3-Oxooxa- and 3-oxoazacycloalk-4-enes were obtained with good yield from 1-(ω-alkenyloxy)- and 1-(ω-alkenylamino)-but-3-en-2-ones by using a ring-closing metathesis. This methodology has been used to synthesize an inhibitor of cathepsin K.

Synthesis of pyranonaphthoquinone antibiotics involving the phthalide annulation strategy

The synthesis of the pyranonaphthoquinone antibiotic pentalongin was performed using the phthalide annulation strategy. Annulation of the cyanophthalide onto 6H-pyran-3-one resulted in a hongconin analogue, which upon further elaboration was converted into the natural product. Georg Thieme Verlag Stuttgart.

Highly enantioselective Cu-catalyzed conjugate additions of dialkylzinc reagents to unsaturated furanones and pyranones: Preparation of air-stable and catalytically active Cu-peptide complexes

(Chemical Equation Presented) The first generally effective method for catalytic asymmetric conjugate addition (ACA) of dialkylzinc reagents to unsaturated furanones and pyranones (see scheme) with different steric and electronic properties is reported. S

Synthesis of 3-oxo oxacycloalkenes by ring closing metathesis

The synthesis of six-, seven- and eight-membered 3-oxo oxacycloalkenes by using ring-closing metathesis has been achieved from 1-(ω-alkenyloxy)-but-3-en-2-ones.