98197-88-7

Basic information

• Product Name: CHEMPACIFIC 38139
• Synonyms: CHEMPACIFIC 38139;(4-NITRO-PYRIDIN-2-YL)-METHANOL;4-NITRO-2-HYDROXYMETHYL-PYRIDINE;2-(Hydroxymethyl)-4-nitropyridine;4-nitro-2-pyridinemethanol;(4-Nitropyridin-2-yl)
• CAS NO: 98197-88-7
• Molecular Formula: C₆H₆N₂O₃
• Molecular Weight: 154.12
• Mol File: 98197-88-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 337.8°C at 760 mmHg
• Flash Point: 158.1°C
• Appearance: /
• Density: 1.422g/cm³
• Vapor Pressure: 3.99E-05mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: CHEMPACIFIC 38139(CAS DataBase Reference)
• NIST Chemistry Reference: CHEMPACIFIC 38139(98197-88-7)
• EPA Substance Registry System: CHEMPACIFIC 38139(98197-88-7)

Safety Data

• Hazardous Substances Data: 98197-88-7(Hazardous Substances Data)

Usage

General Description

CHEMPACIFIC 38139 is a chemical substance that contains a mixture of sodium bromide, zinc bromide, and calcium bromide. These chemicals are commonly used as drilling fluids in the oil and gas industry due to their high density and ability to control pressure and stabilize wellbores. Sodium bromide is a widely used salt with many industrial applications, while zinc bromide and calcium bromide are used for their corrosion inhibition properties and their ability to prevent formation damage in oil and gas wells. Overall, CHEMPACIFIC 38139 is a versatile chemical blend known for its effective performance in drilling operations.

InChI:InChI=1/C6H6N2O3/c9-4-5-3-6(8(10)11)1-2-7-5/h1-3,9H,4H2

Upstream product

• 5470-66-6 2-methyl-4-nitropyridine N-oxide 
• 108-24-7 acetic anhydride 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 103577-65-7 (4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methanol 
• 19677-69-1 (4-ethoxypyridin-2-yl)methanol 
• 16744-81-3 4-methoxypyridine-2-carbaldehyde 
• 771581-04-5 (4-nitro-pyridin-2-yl)methylamine 
• 131747-63-2 4-bromo-2-pyridinecarboxaldehyde 
• 16665-43-3 4-ethoxypicolinaldehyde 
• 16665-38-6 4-methoxy-2-(hydroxymethyl)pyridine 
• 442910-43-2 2-(bromomethyl)-4-nitropyridine 
• 108337-77-5 2-(N-Benzyl-N-methylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(4-nitro-2-pyridyl)-3,5-pyridinedicarboxylate 
• 108338-19-8 4-nitro-2-pyridinecarboxaldehyde 

Relevant articles and documents

A Chiral Lanthanide Tag for Stable and Rigid Attachment to Single Cysteine Residues in Proteins for NMR, EPR and Time-Resolved Luminescence Studies

A lanthanide-binding tag site-specifically attached to a protein presents a tool to probe the protein by multiple spectroscopic techniques, including nuclear magnetic resonance, electron paramagnetic resonance and time-resolved luminescence spectroscopy. Here a new stable chiral LnIII tag, referred to as C12, is presented for spontaneous and quantitative reaction with a cysteine residue to generate a stable thioether bond. The synthetic protocol of the tag is relatively straightforward, and the tag is stable for storage and shipping. It displays greatly enhanced reactivity towards selenocysteine, opening a route towards selective tagging of selenocysteine in proteins containing cysteine residues. Loaded with TbIII or TmIII ions, the C12 tag readily generates pseudocontact shifts (PCS) in protein NMR spectra. It produces a relatively rigid tether between lanthanide and protein, which is beneficial for interpretation of the PCSs by single magnetic susceptibility anisotropy tensors, and it is suitable for measuring distance distributions in double electron–electron resonance experiments. Upon reaction with cysteine or other thiol compounds, the TbIII complex exhibits a 100-fold enhancement in luminescence quantum yield, affording a highly sensitive turn-on luminescence probe for time-resolved FRET assays and enzyme reaction monitoring.

9H-PYRROLO-DIPYRIDINE DERIVATIVES

The invention relates to 9H-pyrrolo-dipyridine derivatives of formula I, processes for preparing them, pharmaceutical compositions containing them and their use as radiopharmaceuticals in particular as imaging agents for the detection of Tau aggregates.

C-H bond oxidation catalyzed by an imine-based iron complex: A mechanistic insight

A family of imine-based nonheme iron(II) complexes (LX)2Fe(OTf)2 has been prepared, characterized, and employed as C-H oxidation catalysts. Ligands LX (X = 1, 2, 3, and 4) stand for tridentate imine ligands resulting from spontaneous condensation of 2-pycolyl-amine and 4-substituted-2-picolyl aldehydes. Fast and quantitative formation of the complex occurs just upon mixing aldehyde, amine, and Fe(OTf)2 in a 2:2:1 ratio in acetonitrile solution. The solid-state structures of (L1)2Fe(OTf)(ClO4) and (L3)2Fe(OTf)2 are reported, showing a low-spin octahedral iron center, with the ligands arranged in a meridional fashion. 1H NMR analyses indicate that the solid-state structure and spin state is retained in solution. These analyses also show the presence of an amine-imine tautomeric equilibrium. (LX)2Fe(OTf)2 efficiently catalyze the oxidation of alkyl C-H bonds employing H2O2 as a terminal oxidant. Manipulation of the electronic properties of the imine ligand has only a minor impact on efficiency and selectivity of the oxidative process. A mechanistic study is presented, providing evidence that C-H oxidations are metal-based. Reactions occur with stereoretention at the hydroxylated carbon and selectively at tertiary over secondary C-H bonds. Isotopic labeling analyses show that H2O2 is the dominant origin of the oxygen atoms inserted in the oxygenated product. Experimental evidence is provided that reactions involve initial oxidation of the complexes to the ferric state, and it is proposed that a ligand arm dissociates to enable hydrogen peroxide binding and activation. Selectivity patterns and isotopic labeling studies strongly suggest that activation of hydrogen peroxide occurs by heterolytic O-O cleavage, without the assistance of a cis-binding water or alkyl carboxylic acid. The sum of these observations provides sound evidence that controlled activation of H2O2 at (LX)2Fe(OTf)2 differs from that occurring in biomimetic iron catalysts described to date.