98223-72-4

Basic information

• Product Name: 4-NAPHTHALEN-1-YL-MORPHOLINE
• Synonyms: 4-NAPHTHALEN-1-YL-MORPHOLINE
• CAS NO: 98223-72-4
• Molecular Formula: C14H15NO
• Molecular Weight: 213.27
• Mol File: 98223-72-4.mol
• Article Data: 64

Chemical Properties

• Melting Point: 83 °C
• Boiling Point: 380.5±35.0 °C(Predicted)
• Appearance: /
• Density: 1.141±0.06 g/cm3(Predicted)
• PKA: 4.32±0.40(Predicted)
• CAS DataBase Reference: 4-NAPHTHALEN-1-YL-MORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-NAPHTHALEN-1-YL-MORPHOLINE(98223-72-4)
• EPA Substance Registry System: 4-NAPHTHALEN-1-YL-MORPHOLINE(98223-72-4)

Safety Data

• Hazardous Substances Data: 98223-72-4(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 86-53-3 1-Cyanonaphthalene 
• 68211-49-4 1-naphthyl tosylate 
• 2216-69-5 1-Methoxynaphthalene 
• 4004-51-7 tri-1-naphthyl phosphate 
• 91-58-7 2-chloronaphthalene 
• 90-13-1 1-Chloronaphthalene 
• 85630-39-3 1-naphthyl N,N-diethylcarbamate 
• 99747-74-7 1-naphthyl triflate 
• 321-38-0 1-Fluoronaphthalene 
• 91-20-3 naphthalene 
• 110210-14-5 4-(2,4-dinitrophenoxy)morpholine 
• 580-13-2 2-bromonaphthalene 
• 13368-42-8 4-(trimethylsilyl)morpholine 

Downstream Products

• 202983-75-3 C₃₁H₃₅N₃O 
• 22871-77-8 5,5-dimethyl-2-(naphthalen-1-yl)-1,3,2-dioxaborinane 

Relevant articles and documents

Amination of Aryl Halides Mediated by Electrogenerated Nickel from Sacrificial Anode

Electrochemical C(sp2)?N couplings mediated by nickel salts generated from the sacrificial anode has been described for the first time. In this approach, the sacrificial nickel anode is employed as the sole source of nickel and the process, operationally simple to set up, enables the preparation of functionalized arylamine derivatives with moderate to good yields, under mild reaction conditions and without additional ligand. A cooperative process between the two electrodes is involved in the proposed mechanism.

Pyrazolyl bistriazolyl phosphine compound and application of pyrazolyl bistriazolyl phosphine compound

The invention discloses a pyrazolyl bistriazolyl phosphine compound and application thereof. The invention discloses a compound shown as a formula I. In the formula I, R1 is hydrogen, C1-C6 alkyl or phenyl; R2 and R3 are phenyl; R4 and R5 are independently a C1-C6 alkyl group, a C3-C8 cycloalkyl group, or a phenyl group. The pyrazolyl bistriazolyl phosphine compound disclosed by the invention is stable in property, excellent in catalytic effect and high in selectivity, and can be applied to catalytic coupling of amine, boric acid compounds and halides.

Nickel-Catalyzed Decarbonylative Amination of Carboxylic Acid Esters

The reaction of carboxylic acid derivatives with amines to form amide bonds has been the most widely used transformation in organic synthesis over the past century. Its utility is driven by the broad availability of the starting materials as well as the kinetic and thermodynamic driving force for amide bond formation. As such, the invention of new reactions between carboxylic acid derivatives and amines that strategically deviate from amide bond formation remains both a challenge and an opportunity for synthetic chemists. This report describes the development of a nickel-catalyzed decarbonylative reaction that couples (hetero)aromatic esters with a broad scope of amines to form (hetero)aryl amine products. The successful realization of this transformation was predicated on strategic design of the cross-coupling partners (phenol esters and silyl amines) to preclude conventional reactivity that forms inert amide byproducts.