98369-91-6Relevant academic research and scientific papers
A NOVEL METHOD FOR THE GEMINAL DIALKYLATION OF THE CARBONYL GROUP OF AROMATIC ALDEHYDES AND KETONES
Clarembeau, M.,Krief, A.
, p. 1719 - 1722 (2007/10/02)
The title transformation is efficiently achieved by using the selenium methodology which involves the sequential reductive alkylation of arylselenoacetals and of benzylselenides.
METALLATION OF BENZYL SELENIDES AND OF α-ARYL SELENOACETALS. SCOPE AND LIMITATIONS.
Clarembeau, M.,Krief, A.
, p. 1723 - 1726 (2007/10/02)
α-Metallo benzylselenides and α-metallo selenoacetals derived from aromatic aldehydes have been conveniently prepared by metallation of the corresponding carbon acids.KDA in THF proved among the various basic systems tested, the most efficient.
Novel Synthetic Route to Aryl Alkanes from Aromatic Aldehydes and Ketones. Novel Geminal Dialkylation of the Carbonyl Group of Aromatic Aldehydes and Ketones
Krief, Alain,Clarembeau, M.,Barbeaux, Ph.
, p. 457 - 458 (2007/10/02)
Benzyl-lithiums, readily available from benzyl methyl selenides and alkyl-lithiums, are efficiently alkylated; this reaction allows the geminal dialkylation of the carbonyl groups of aromatic aldehydes and ketones and the geminal aryl-alkylation of aliphatic analogues.
