98442-51-4

Upstream product

• 74-90-8 hydrogen cyanide 
• 19722-76-0 methyl-2,6-dihydroxy-4-methoxybenzoate 
• 557-21-1 dicyanozinc 
• 83-30-7 acide 2,4,6-trihydroxybenzoique 
• 68-12-2 N,N-dimethyl-formamide 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 51116-97-3 methyl 3-formyl-2,4,6-trimethoxybenzoate 
• 118093-03-1 3-formyl-2,6-dihydroxy-4-methoxy-5-methyl-benzoic acid methyl ester 
• 118093-05-3 2-methoxy-3-methyl-4,6-dihydroxybenzaldehyde 
• 125536-25-6 7-hydroxy-5-methoxy-6-methyl-2-phenyl-1-benzopyrylium perchlorate 
• 3519-76-4 2,4-dihydroxy-6-methoxybenzaldehyde 
• 39828-25-6 5-methoxyflavan-7-ol 
• 21722-30-5 methyl 4-methoxy-3,5-dimethylphloroglucinol carboxylate 
• 5071-56-7 2,6-Dihydroxy-3-hydroxymethyl-4-methoxy-benzoesaeure-methylester 
• 51116-98-4 6-((Z)-3,7-Dimethyl-octa-2,6-dienyloxy)-3-formyl-2-hydroxy-4-methoxy-benzoic acid methyl ester 
• 39828-28-9 2,6-Dihydroxy-4-methoxy-3-methyl-benzoesaeure-methylester 
• 51117-01-2 6-((Z)-3,7-Dimethyl-octa-2,6-dienyloxy)-2-hydroxy-3-hydroxymethyl-4-methoxy-benzoic acid methyl ester 
• 51117-03-4 Methyl-3-Formyl-6-hydroxy-2,4-dimethoxybenzoat 

Relevant academic research and scientific papers

Enantioselective Total Synthesis of Berkeleyone A and Preaustinoids

Herein we report the first enantioselective total synthesis of 3,5-dimethylorsellinic acid-derived meroterpenoids (?)-berkeleyone A and its five congeners ((?)-preaustinoids A, A1, B, B1, and B2) in 12–15 steps, starting from commercially available 2,4,6-trihydroxybenzoic acid hydrate. Based upon the recognition of latent symmetry within D-ring, our convergent synthesis features two critical reactions: 1) a symmetry-breaking, diastereoselective dearomative alkylation to assemble the entire carbon core, and 2) a Sc(OTf)3-mediated sequential Krapcho dealkoxycarbonylation/carbonyl α-tert-alkylation to forge the intricate bicyclo[3.3.1]nonane framework. We also conducted our preliminary biomimetic investigations and uncovered a series of rearrangements (α-ketol, α-hydroxyl-β-diketone, etc.) responsible for the biomimetic diversification of (?)-berkeleyone A into its five preaustinoid congeners.

Biomimetic Synthesis of Complex Flavonoids Isolated from Daemonorops “Dragon's Blood”

The dragonbloodins are a pair of complex flavonoid trimers that have been isolated from the palm tree Daemonorops draco, one of the sources of the ancient resin known as “dragon's blood”. We present a short synthesis that clarifies their relative configur

Trimethoxyphenyl Compounds, XI. Constituents of Hagenia abyssinica, 2: Synthesis of Phloracylophenones Containing One Phloroglucinol Unit

For the Koso constituents K6 and K8, we previously proposed the structures 1a, b and 2a, b.These assignments have been confirmed by synthesis. - Keywords: Flores koso, Revised Structure, Synthesis of Phloroglucinols