3519-76-4Relevant academic research and scientific papers
Identification of 7,4′-dihydroxy-5-methoxyflavylium in "dragon's blood": To be or not to be an anthocyanin
Melo, Maria J.,Sousa, Micaela,Parola, A. Jorge,De Melo, J. Sergio Seixas,Catarino, Fernando,Marcalo, Joaquim,Pina, Fernando
, p. 1417 - 1422 (2007)
The compound 7,4′-dihydroxy-5-methoxyflavylium (dracoflavylium) was identified as the major red colorant in samples of the resin "dragon's blood", extracted from the tree Dracaena draco. The complex network of reversible chemical reactions that dracoflavy
Biomimetic Synthetic Studies on the Bruceol Family of Meroterpenoid Natural Products
Day, Aaron J.,George, Jonathan H.,Sumby, Christopher J.
, (2020/02/04)
A biomimetic approach to total synthesis can offer several benefits, including the development of cascade reactions for the rapid generation of molecular complexity, and guidance in the structure revision of old natural products and the anticipation of ne
Biomimetic Synthesis of Complex Flavonoids Isolated from Daemonorops “Dragon's Blood”
Schmid, Matthias,Trauner, Dirk
, p. 12332 - 12335 (2017/09/25)
The dragonbloodins are a pair of complex flavonoid trimers that have been isolated from the palm tree Daemonorops draco, one of the sources of the ancient resin known as “dragon's blood”. We present a short synthesis that clarifies their relative configur
1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS
-
Page/Page column 141, (2014/10/03)
Provided are compounds useful for controlling endoparasites both in animals and agriculture. Further provided are methods for controlling endoparasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling endoparasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier. The claimed compounds are described by the following Markush formula:A typical example for a compound according to above formula is: A typical example for a compound according to above formula is:
4'-Methyl derivatives of 5-MOP and 5-MOA: Synthesis, photoreactivity, and photobiological activity
Gia, Ornella,Anselmo, Antonella,Conconi, Maria Teresa,Antonello, Cipriano,Uriarte, Eugenio,Caffieri, Sergio
, p. 4489 - 4496 (2007/10/03)
The synthesis and photobiological activity of four new 4'-methyl derivatives of 5-MOP (5-methoxypsoralen) and 5-MOA (5-methoxyangelicin), i.e., 4,4'-dimethyl-5-methoxypsoralen, 3,4'-dimethyl-5-methoxypsoralen, 4,4'- dimethyl-5-methoxyangelicin, and 3,4'-dimethyl-5-methoxyangelicin, are described. All these compounds photobind efficiently to DNA. The DNA- photobinding process was investigated using various nucleic acid structures such as double-helix DNA, bacterial DNA, and synthetic polydeoxyribonucleotides. Photoreaction experiments showed that, unlike 8- MOP (8-methoxypsoralen) and 5-MOP, both angular derivatives bind thymine and cytosine with the same efficiency. The principal nucleoside-psoralen monoadducts were isolated and characterized after enzymatic digestion or acid hydrolysis. Biological activity studies revealed a good correlation with the extent of covalent photoaddition. Moreover, the two angular derivatives and the 4,4'-dimethyl-5-methoxypsoralen were unable to induce skin erythema, in striking contrast with the reference drugs, 8-MOP and 5-MOP; only the 3,4'- dimethyl-5-methoxypsoralen caused erythema, although to a substantially lower extent than that induced by the two parent compounds.
Trimethoxyphenyl Compounds, XI. Constituents of Hagenia abyssinica, 2: Synthesis of Phloracylophenones Containing One Phloroglucinol Unit
Schiemenz, Guenter Paulus,Behrens, Heinz,Ebert, Claus Peter,Maienschein, Konrad,Schroeder, Jens-Michael
, p. 681 - 692 (2007/10/02)
For the Koso constituents K6 and K8, we previously proposed the structures 1a, b and 2a, b.These assignments have been confirmed by synthesis. - Keywords: Flores koso, Revised Structure, Synthesis of Phloroglucinols
Effect of Substituents in the 5' and 7' Positions on the Spectra of Merocyanines of 1,3,3-Trimethyl-6'-nitroindoline-2-spiro-2'--chromenes
Gal'bershtam, M. A.,Samoilova, N. P.,Bobyleva, G. K.
, p. 352 - 356 (2007/10/02)
The corresponding photochromic 5',7'-disubstituted indolinospirochromenes were obtained by the reaction of 4,6-dialkoxy-5-nitrosalicylaldehydes, as well as 4,6-dimethyl-5-nitrosalicylaldehyde, with 1,3,3-trimethyl-2-methyleneindoline.Bulky electron-donor
