98516-10-0

Basic information

• Product Name: Acetic acid (1R,6S)-6-hydroxymethyl-cyclohex-3-enylmethyl ester
• CAS NO: 98516-10-0
• Molecular Weight: 184.235
• Mol File: 98516-10-0.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Acetic acid (1R,6S)-6-hydroxymethyl-cyclohex-3-enylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (1R,6S)-6-hydroxymethyl-cyclohex-3-enylmethyl ester(98516-10-0)
• EPA Substance Registry System: Acetic acid (1R,6S)-6-hydroxymethyl-cyclohex-3-enylmethyl ester(98516-10-0)

Safety Data

• Hazardous Substances Data: 98516-10-0(Hazardous Substances Data)

Upstream product

• 439919-46-7 cis-1,6-dihydroxymethyl-3-cyclohexene 
• 4841-84-3 dimethyl cis-1,2,3,6-tetrahydrophthalate 
• 108-24-7 acetic anhydride 
• 954148-36-8 (1R,2S)-[2-[(acetyloxy)methyl]cyclohex-4-en-1-yl]methyl acetate 
• 141-78-6 ethyl acetate 
• 935-79-5 cis-1,2,3,6-tetrahydrophthalic anhydride 
• 79-20-9 acetic acid methyl ester 
• 108-05-4 vinyl acetate 
• 13287-81-5 4,5-bis(hydroxymethyl)-1-cyclohexene 

Downstream Products

• 1356956-20-1 C₂₀H₃₀O₆S 
• 1356956-19-8 C₂₀H₃₀O₆S 
• 1356956-18-7 C₁₁H₁₅NO₂ 
• 483-26-1 (-)-alloyohimbane 
• 174152-17-1 Acetic acid (1S,6R)-6-(diethoxy-phosphorylmethyl)-cyclohex-3-enylmethyl ester 
• 174152-14-8 Acetic acid (1S,2R)-2-(diethoxy-phosphorylmethyl)-cyclohexylmethyl ester 
• 174152-18-2 Acetic acid (1S,6R)-6-formyl-cyclohex-3-enylmethyl ester 
• 1262482-52-9 (3aS,4S,7aR)-hexahydro-2H-furo[2,3-b]pyran-4-yl-(2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl carbamate 
• 523-06-8 yohimbane 

Relevant articles and documents

TRICYCLIC P2-LIGAND CONTAINING POTENT HIV-PROTEASE INHIBITORS

Compounds of formula (I), pharmaceutical compositions comprising compounds of the formula (I), and methods of treating an HIV infection comprising administering an effective amount of one or more compounds of formula (I), or a pharmaceutical composition comprising same.

An enantioselective enzymatic desymmetrization route to hexahydro-4H-furopyranol, a high-affinity ligand for HIV-1 protease inhibitors

An enantioselective synthesis of (3aS,4S,7aR)-hexahydro-4H-furo[2,3-b]pyran-4-ol, a high-affinity nonpeptide ligand for a variety of potent HIV-1 protease inhibitors is described. The key steps involved a highly enantioselective enzymatic desymmetrization

Access to the akuammiline family of alkaloids: Total synthesis of (+)-scholarisine A

The planning and implementation of an enantioselective total synthesis of (+)-scholarisine A is presented. Key tactics employed include a novel cyclization, consisting of a nitrile reduction coupled with concomitant addition of the resultant amine to an epoxide; a modified Fischer indolization; an oxidative lactonization of a diol in the presence of an indole ring; and a late-stage cyclization to complete the caged ring scaffold. The development of a possible "retro-biosynthetic" approach to other members of the akuammiline alkaloid family is also described.