98533-06-3

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 98533-08-5 4-N-(N-methylpyrrolidin-2-ylidene)-2’-deoxycytidine 
• 872-50-4 1-methyl-pyrrolidin-2-one 
• 39650-82-3 2,2-dimethoxy-1-methylpyrrolidine 

Downstream Products

• 172033-38-4 1-[(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(2-thioxo-2λ⁵-[1,3,2]dithiaphospholan-2-yloxy)-tetrahydro-furan-2-yl]-4-[1-methyl-pyrrolidin-(2Z)-ylideneamino]-1H-pyrimidin-2-one 
• 76512-82-8 5'-O-(4,4'-dimethoxytrityl)deoxycytidine 

Relevant academic research and scientific papers

PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF

Aspects of the present disclosure include compositions that make use of phosphorus and/or nucleobase protecting groups which find use in the synthesis of long polynucleotides. Phosphorus protecting groups are provided that help increase the stepwise coupl

Amidine Protecting Groups for Oligonucleotide Synthesis

Amidines have been investigated for protection of deoxyadenosine, deoxycytidine, 5-methyldeoxycytidine, cytidine, and deoxyguanosine.These amidine-protected nucleosides and their 5'-bis(p-anisylphenyl)methyl derivatives were prepared in high yield (79-100