98627-35-1Relevant academic research and scientific papers
To the methoxy ethyl phenol synthesis method (by machine translation)
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, (2018/11/04)
The invention discloses a method for synthesizing methoxy ethyl phenol, to the chlorophenol as the starting material, through the phenolic hydroxyl protection, format reaction, methylation and hydrogenation debenzylation reaction to obtain the target product to the methoxy ethyl phenol process, the methylation reaction is just a simple filtering operation that can be used for the next step reaction, without any other operation. This invention adopts the [...] as the starting material to synthesize to methoxy ethyl phenol, reduce the difficulty of after treatment, reduce the reaction time, the product has high purity, high yield, good stability of the product. (by machine translation)
Preparation and antioxidant activity of tyrosyl and homovanillyl ethers
Madrona,Pereira-Caro,Bravo,Mateos,Espartero
experimental part, p. 1169 - 1178 (2012/05/05)
Preparation of tyrosyl and homovanillyl lipophilic derivatives was carried out as a response to the food industry's increasing demand for new synthetic lipophilic antioxidants. Tyrosyl and homovanillyl ethers were synthesized in high yields by a three-step procedure starting from tyrosol (Ty) and homovanillic alcohol (HMV). The antioxidant activity of these new series of alkyl tyrosyl and homovanillyl ethers was evaluated by the Rancimat test in a lipophilic food matrix and by the FRAP, ABTS and ORAC assays and compared to free Ty and HMV as well as two antioxidants widely used in the food industry, butylhydroxytoluene (BHT) and α-tocopherol. The results pointed out the higher activity of homovanillyl series in comparison with tyrosyl series with all the assayed methods. However, while both synthetic series were less antioxidant than BHT and α-tocopherol in a lipophilic matrix after their Rancimat test evaluation, homovanillyl alkyl ethers showed the best reducing power and radical scavenging activity of all evaluated compounds. This batch of synthetic lipophilic compounds, derived from biologically active compounds such as Ty and HMV, provide interesting and potentially bioactive compounds.
The evaluation of a biogenetically based approach to the synthesis of octahydro-1H-benzofuro[3,2-e]isoquinolines
Ajao,Bird,Chauhan
, p. 1367 - 1372 (2007/10/02)
A potential synthetic route to octahydro-1H-benzofuro[3,2-e]isoquinoline derivatives by intermolecular oxidative phenolic coupling has been studied. A variety of successful coupling reactions have been effected between 2-naphthol or 4-t-butylphenol and p-cresol, 2-(p-hydroxyphenyl)ethanol, 3,4-dimethylphenol, 5-indanol and 6-hydroxytetralin, but 2-acetyl-7-hydroxytetrahydroisoquinoline failed to participate in such reactions.
