98674-79-4

Basic information

• Product Name: (+/-)-2,2-dimethyl-1-phenyl-1,3-propanediol
• Synonyms: 2,2-dimethyl-1-phenyl-1,3-propanediol
• CAS NO: 98674-79-4
• Molecular Formula: C11H16O2
• Molecular Weight: 180.24
• Mol File: 98674-79-4.mol
• Article Data: 23

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (+/-)-2,2-dimethyl-1-phenyl-1,3-propanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-2,2-dimethyl-1-phenyl-1,3-propanediol(98674-79-4)
• EPA Substance Registry System: (+/-)-2,2-dimethyl-1-phenyl-1,3-propanediol(98674-79-4)

Safety Data

• Hazardous Substances Data: 98674-79-4(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 24, p. 4287, 1983 DOI: 10.1016/S0040-4039(00)88322-7

Upstream product

• 100-52-7 benzaldehyde 
• 78-84-2 isobutyraldehyde 
• 1479042-96-0 (6S,3E)-6-hydroxy-5,5-dimethyl-6-phenylhex-3-enoic acid dimethylamide 
• 133271-06-4 (S)-(+)-3-phenyl-3-hydroxy-2,2-dimethylpropanal 
• 108-05-4 vinyl acetate 
• 33950-46-8 1-phenyl-2,2-dimethyl-1,3-propanediol 
• 56010-63-0 2,2-dimethyl-3-hydroxy-1-phenylpropan-1-one 
• 1273614-88-2 (S)-2,2-dimethyl-1-phenyl-1,3-propanediol 3-O-benzoate 
• 1372861-85-2 (S)-2,2-dimethyl-1-phenyl-1,3-propanediol 3-O-pivaloate 
• 88903-20-2 3-hydroxy-2,2-dimethyl-3-phenylpropanal 
• 90507-55-4 (R)-((S)-2,2-Dimethyl-3-oxo-1-phenyl-propoxy)-phenyl-acetic acid 
• 90581-54-7 (2R,5R)-2,5-Diphenyl-[1,3]dioxolan-4-one 
• 90507-71-4 (R)-(-)-3-phenyl-3-hydroxy-2,2-dimethylpropanal 
• 98674-80-7 (R)-(-)-5,5-dimethyl-2-hydroxy-4-phenyl-1,3,2-dioxaphosphorinane 2-oxide 

Downstream Products

• 98674-80-7 (R)-(-)-5,5-dimethyl-2-hydroxy-4-phenyl-1,3,2-dioxaphosphorinane 2-oxide 
• 98674-81-8 (S)-(+)-5,5-dimethyl-2-hydroxy-4-phenyl-1,3,2-dioxaphosphorinane 2-oxide 
• 24632-19-7 3,3-dimethyl-2-phenyloxetane 
• 100612-73-5 3-acetoxy-2,2-dimethyl-1-phenyl-propan-1-one 
• 101499-58-5 1,3-diacetoxy-2,2-dimethyl-1-phenyl-propane 
• 121108-77-8 5,5-dimethyl-4-phenyl-1,3-dioxane 

Relevant articles and documents

Phosphine-oxide-catalyzed Enantioselective Cross-aldol Reactions of Aldehydes with Trichlorosilane as Lewis Acid Promoter

A hypervalent silicon complex between trichlorosilane and a chiral phosphine oxide acts as an effective Lewis acid mediator that successfully promotes highly enantioselective cross-aldol reactions between two aldehydes. The high yielding transformation is

Phosphinous Acid Platinum Complex as Robust Catalyst for Oxidation: Comparison with Palladium and Mechanistic Investigations

Secondary phosphine oxides proved to be effective preligands to stabilise a hydroxy-platinum based catalyst that allows the aerobic/anaerobic oxidation of challenging substrates. Kinetic comparisons showed that this system is more efficient and stable than previously reported similar palladium-based catalysts. A neutral platinum dimer bearing bridging hydroxy ligands has been isolated and fully characterised by X-ray diffraction and its involvement in the mechanism has been evidenced by mechanistic studies.

A method for preparing chiral ring phosphoric acid (by machine translation)

The invention discloses a method for preparing chiral ring of phosphoric acid, the method comprises the following steps: a Isobutyraldehyde, aromatic aldehyde under the condition of chiral catalyst to catalyze the reaction generating chiral 3-aryl-3-hydroxy -2,2-dimethyl-propionaldehyde; chiral b 3-aryl-3-hydroxy -2,2-dimethyl propionic aldehyde reduction to obtain chiral 1-aryl -2,2-dimethyl -1,3-propylene glycol; c in methylene chloride under the conditions of reaction with phosphorus oxychloride to obtain chiral 4-aryl-2-chloro -5,5-dimethyl-2-oxo -1, 3, 2-dioxo-phosphorus heterocycle hexane chloride; in d hydrolysis under alkaline conditions, dyeworks generating chiral ring phosphoric acid. The high optical purity of the target product, the operation is simple, low cost, high yield, less pollution, belonging to the field of organic synthesis. (by machine translation)