989-38-8 Usage
Description
Basic Red 1, also known as Rhodamine 6G, is an organic laser dye that is highly fluorescent and can be used with various alternate light sources. It is one of the most effective laser dyes in recovering latent prints on various non-porous surfaces and can also be used on porous or semi-porous surfaces under certain conditions.
Uses
Used in Forensic Science:
Basic Red 1 is used as a fluorescent dye for recovering latent prints on non-porous surfaces, as it is highly efficient and can be used with various alternate light sources.
Used in Biotechnology Applications:
Basic Red 1 is used as a fluorescence tracker in various biotechnology applications such as fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy, and ELISA. It helps in defining the spectroscopic characteristics for achieving a high conversion efficiency and precision of measurements.
Used in Cell Biology Research:
Basic Red 1 is used as a leukocyte marker to study the interaction between leukocytes and the vascular endothelium. It is also used to label platelets, enabling researchers to track and visualize these cells in various experiments.
Used in Fluorescence Spectroscopy:
Basic Red 1 is used as a probe in fluorescence spectroscopy due to its high quantum yield for fluorescence. The absorption of Basic Red 1 in different solvents can range between 400-700 nm, making it a versatile tool for studying various chemical and physical properties.
Preparation
3-(Ethylamino)-4-methylphenol and Phthalic anhydride to afford the product was obtained ethanol and an inorganic acid esterification; O-Methylaniline with ethylene oxide Alkylation , sulfonated, alkali fusion, and Phthalic anhydride condensation, and then use ethylene oxide esterification.
Air & Water Reactions
Insoluble in water.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition Basic Red 1 emits very toxic fumes.
Fire Hazard
Flash point data for Basic Red 1 are not available. Basic Red 1 is probably combustible.
Flammability and Explosibility
Notclassified
Biological Activity
Rhodamine 6G is a rhodamine analog useful in P-glycoprotein (Pgp) efflux assays. It has been used to characterize kinetics of multidrug resistance protein 1 (MRP1)-mediated efflux.A rhodamine analog useful in Pgp efflux assays. Has been used to characterize kinetics of MRP1- mediated efflux.
Biochem/physiol Actions
Rhodamine 6G is a rhodamine analog useful in P-glycoprotein (Pgp) efflux assays. It has been used to characterize kinetics of multidrug resistance protein 1 (MRP1)-mediated efflux.
Safety Profile
Poison by ingestion and intraperitoneal routes. An experimental teratogen. Mutation data reported. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits very toxic fumes of Cland NOx.
Fading
Stain
ISO
2
Purification Methods
Crystallise the dye from MeOH or EtOH, and dry it in a vacuum oven. [Beilstein 18 III/IV 8244, 18/12 V 283.]
Check Digit Verification of cas no
The CAS Registry Mumber 989-38-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,8 and 9 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 989-38:
(5*9)+(4*8)+(3*9)+(2*3)+(1*8)=118
118 % 10 = 8
So 989-38-8 is a valid CAS Registry Number.
InChI:InChI=1/C28H30N2O3/c1-6-29-23-15-25-21(13-17(23)4)27(19-11-9-10-12-20(19)28(31)32-8-3)22-14-18(5)24(30-7-2)16-26(22)33-25/h9-16,29H,6-8H2,1-5H3/b30-24+