98925-54-3

Upstream product

• 100-39-0 benzyl bromide 
• 51548-88-0 (+/-)-1,2:4,5-di-O-isopropylidene-myo-inositol 
• 34361-60-9 1,2:4,5-dicyclohexylidene-myo-inositol 
• 87-89-8 D-myo-inositol 
• 111392-18-8 (+/-)-1,3,4-tri-O-allyl-5,6-di-O-benzyl-myo-inositol 
• 111392-09-7 (+/-)-1,3,4-Tri-O-allyl-2-O-benzyl-myo-inositol 
• 140886-97-1 C₄₂H₅₄O₁₂ 
• 98906-37-7 (3aR,4S,5S,6S,7S,7aR)-4,5,7-Tris-allyloxy-6-benzyloxy-2,2-dimethyl-hexahydro-benzo[1,3]dioxole 
• 136986-26-0 rac-1,3,4-Tri-O-allyl-5,6-O-isopropylidene-myo-inositol 
• 141040-49-5 (1S,2S,3R,4S,5R,6R)-3,4,6-Tris-allyloxy-5-benzyloxy-cyclohexane-1,2-diol 
• 98906-34-4 (±)-2,3-O-isopropylidene-1,4-di-O-allyl-6-O-benzyl-myo-inositol 
• 98906-33-3 (±)-1,4-di-O-allyl-2,3-O-isopropylidene-myo-inositol 
• 98906-32-2 (±)-1,4-di-O-allyl-2,3:5,6-di-O-isopropylidene-myo-inositol 
• 98906-26-4 (3aR,4R,5S,6S,7R,7aS)-5,6-Bis-allyloxy-4,7-bis-benzyloxy-2,2-dimethyl-hexahydro-benzo[1,3]dioxole 

Downstream Products

• 140886-99-3 Phosphorous acid dibenzyl ester (1R,2S,3S,4R,5R,6R)-2,3,6-tris-benzyloxy-4,5-bis-(bis-benzyloxy-phosphanyloxy)-cyclohexyl ester 
• 140887-03-2 Phosphoric acid benzyl ester (1R,2S,3S,4R,5R,6R)-2,3,6-tris-benzyloxy-4,5-bis-(benzyloxy-hydroxy-phosphoryloxy)-cyclohexyl ester 
• 141116-53-2 C₄₈H₄₈O₁₅P₃^(3-)*3Na⁽¹⁺⁾ 
• 114419-09-9 (-)-1L-2,5,6-tri-O-benzyl-1,3,4-tris(dibenzylphospho)-myo-inositol 
• 114419-08-8 (+)-1L-2,5,6-tri-O-benzyl-myo-inositol 
• 80971-00-2 (3aR,4S,5S,6R,7S,7aR)-4,5,7-Tris-benzyloxy-6-methoxy-2,2-dimethyl-hexahydro-benzo[1,3]dioxole 
• 111446-91-4 (+/-)-1,2,4-tri-O-benzyl-5,6-O-isopropylidene-myo-inositol 
• 80971-02-4 (1S,2S,3R,4S,5S,6R)-3,4,6-Tris-benzyloxy-5-methoxy-cyclohexane-1,2-diol 
• 98906-30-0 (±)-2,3,6-tri-O-benzyl-myo-inositol 
• 114342-70-0 DL-2,5,6-tri-O-benzyl-1,3,4-tris(dibenzylphospho)-myo-inositol 
• 98906-30-0 (+/-)-2,5,6-tri-O-benzyl-myo-inositol 

Relevant academic research and scientific papers

Synthesis and in vitro anticancer activity evaluation of novel bioreversible phosphate inositol derivatives

The chemistry and biology of phosphorylated inositols have become intense areas of research during the last two decades due to their involvement in various cellular signaling processes. However, the metabolic instability by phosphatases or kinases and poo

The preparation of racemic and enantiomerically pure myo-inositol derivatives as intermediates for the synthesis of phosphatidylinositol 3-, 3,4-bis-, and 3,4,5-tris-phosphates and for the synthesis of analogues of 1D-myo-inositol 1,3,4,5-tetrakisphosphat

Details of the products obtained by the tin-mediated allylation and benzylation of 1,2-O-isopropylidene-myo-inositol, which were previously described in a preliminary communication, are provided here. Some of the products from these reactions, particularl

The alkylation of dibutylstannylene derivatives of 1,2-O-isopropylidene-myo-inositol

Benzylation (or allylation) of 1,2-O-isopropylidene-myo-inositol in the presence of an excess of dibutyltin oxide gives, as major products, the readily isolable 3,4,6- (12) and 3,5,6-tri-O-alkyl (13) derivatives which are valuable intermediates for the synthesis of inositol phosphates of the phosphates of the phosphatidylinositol cycle.

Efficient chemoenzymatic synthesis of D-myo-inositol 1,4,5-triphosphate, D-myo-inositol 1,3,4-triphosphate, and D-myo-inositol 1,3,4,5-tetraphosphate

Multigram quantities of Ins(1,4,5) P3, Ins(1,3,4) P3, and Ins(1,3,4,5)P4 are prepared in their enantiomerically pure forms from the two enantiomers of 1,2:5,6-di-O-cyclohexylidene myo-inositol. Also, a facile enzymatic preparation is also described of these chiral precursors through enantiospecific deacylation of the corresponding racemic esters is disclosed.

The preparation, resolution, and phosphorylation of some benzyl ethers of myo-inositol: Intermediates for the synthesis of myo-inositol phosphates of the phosphatidylinositol cycle

The syntheses of the following chiral compounds are described: 1D-2,3,6-tri-, 1D-2,4,5-tri, 1D-2,5,6-tri-, 1D-1,2,3,4-tetra, 1D-1,2,3,6-tetra-, 1D-1,2,4,5-tetra-, and 1D-2,3,5,6-tetra-0-benzyl-myo-inositol; and 1D-2,5,6-tri-0-benzyl-1-0-p-methoxybenyl- an

THE TOTAL SYNTHESIS OF myo-INOSITOL POLYPHOSPHATES

Total synthesis of the individual enentiomers of myo-inositol 4-phosphate (15), myo-inositol 1,4-biphosphate (2) and myo-inositol 1,4,5-triphosphate (1), together with syntheses of racemic myo-inositol 1,3,4-triphosphate (4) and myo-inositol 2,4,5-triphos

The Allyl Group for Protection in Carbohydrate Chemistry. Part 18. Allyl and Benzyl Ethers of myo-Inositol. Intermediates for the Synthesis of myo-Inositol Triphosphates

Racemic 1,2:4,5-di-O-isopropylidene-myo-inositol was converted into racemic 1,2,4-tri-O-benzyl-myo-inositol, 1,2,4-tri-O-p-methoxybenzyl-myo-inositol and 2,4,5-tri-O-benzyl-myo-inositol using allyl groups for 'temporary' protection.The benzyl ethers are required as intermediates for the synthesis of the 'second messenger', inositol 1,4,5-triphosphate and its metabolite, inositol 1,3,4-triphosphate. 1,2,3,4-Tetra-O-benzyl-myo-inositol, and its two monoallyl and monoprop-1-enyl ethers, were also prepared as model compounds for phosphorylation studies of the vicinal 5,6-diol system which occurs in 1,2,4-tri-O-benzyl-myo-inositol.

SYNTHESIS OF RACEMIC MYO-INOSITOL 1,3,4-TRIPHOSPHATE VIA A PHOSPHITE-TRIESTER APPROACH

Phosphitylation of (+/-)- 2,4,5-tri-O-benzyl-myo-Inositol with bis(2-cyanoethyl)chlorophosphine gave, after oxidation followed by basic hydrolysis and subsequently hydrogenolysis, (+/-)-myo-Inositol 1,3,4-triphosphate.