99298-06-3Relevant articles and documents
Design and synthesis of photoaffinity-labeling ligands of the L-prolyl-L-leucylglycinamide binding site involved in the allosteric modulation of the dopamine receptor
Fisher, Abigail,Mann, Amandeep,Verma, Vaneeta,Thomas, Nancy,Mishra, Ram K.,Johnson, Rodney L.
, p. 307 - 317 (2007/10/03)
Pro-Leu-Gly-NH2 (PLG), in addition to its endocrine effects, possesses the ability to modulate dopamine 02 receptors within the central nervous system. However, the precise binding site of PLG is unknown. Potential photoaffinity-labeling ligand
Synthesis and biological activity of iodinated and photosensitive derivatives of tetrabenazine
Aranda,Beaucourt,Ponchant,Isambert,Henry
, p. 369 - 374 (2007/10/02)
The synthesis of a photosensitive iodinated derivative of tetrabenazine, which should be able to lead to the identification of the vesicular catecholamine transporter of adrenal medulla by photoaffinity, is described in detail. The biological activity of this iodinated ligand was found to be significantly lower than that of non iodinated ligands.
IODINATION OF PHENOLS USING CHLORAMINE T AND SODIUM IODIDE
Kometani, Tadashi,Watt, David S.,Ji, Tae
, p. 2043 - 2046 (2007/10/02)
A convenient procedure for the iodination of many substituted phenols uses chloramine T and sodium iodide in DMF, DMSO, or acetonitrile.