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Tris(2-(salicylideneamino)ethyl)amine, also known as TSAE, is a complex organic compound with the chemical formula C21H21N3O3. It is a tridentate ligand, meaning it can form three coordinate bonds with a central metal ion, and is often used in coordination chemistry to create stable metal complexes. TSAE is derived from the condensation of tris(2-aminoethyl)amine with salicylaldehyde, resulting in a compound that has three salicylideneimine groups attached to the nitrogen atoms. This structure endows TSAE with the ability to chelate metal ions, making it a useful agent in various chemical and biological applications, such as in the synthesis of catalysts, sensors, and medicinal compounds. The compound's chelating properties allow it to selectively bind to certain metals, influencing their reactivity and stability.

99315-94-3

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99315-94-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 99315-94-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,3,1 and 5 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 99315-94:
(7*9)+(6*9)+(5*3)+(4*1)+(3*5)+(2*9)+(1*4)=173
173 % 10 = 3
So 99315-94-3 is a valid CAS Registry Number.

99315-94-3Relevant academic research and scientific papers

Synthesis, spectral characterization, and luminescence properties of a cup-like ligand and its magnesium(II) complex

Tai, Xi-Shi,Zhao, Wen-Hua

, p. 2075 - 2082 (2014)

A new tripodal ligand, N,N,N-tri(salicylaldehyde)triaminotriethylamine (1) has been synthesized and characterized by elemental analysis, IR and UV spectroscopy, MS, and X-ray crystallography. X-ray diffraction analysis reveals that the three chains of the

Evaluation of trimetallic Ru(II)- and Os(II)-Arene complexes as potential anticancer agents

Makhubela, Banothile C.E.,Meyer, Mervin,Smith, Gregory S.

, p. 229 - 241 (2014)

Schiff-base ligands, tris-2-(salicylaldimine ethyl)amine and tris-2-(2-pyridylimine ethyl)amine (1 and 2) were prepared and complexed to Ru(II) and Os(II) entities to form new trimetallic complexes (3-10). The complexes are air- and moisture-stable and ha

Attemted Functionalisation of a Mononuclear Barium Complex of a 24-Membered Bibracchial Tetraimine Schiff-base Macrocycle derived from Tris(2-aminoethyl)amine using Salicylaldehyde

Bailey, Neil A.,Barbarin, Cecilia O. Rodriguez de,Fenton, David E.,Hellier, Paul C.,Hempstead, Paul D.,et al.

, p. 765 - 770 (1995)

Functionalisation of a mononuclear barium complex of a 24-membered bibracchial tetraimine Shiff-base macrocycle (L1) derived from the barium-templated cyclocondensation of 2,6-diacetylpyridine and tris(2-aminoethyl)amine was attempted using salicylaldehyde.The reaction leads to the isolation of the tripodal ligand trisamine (L2) and the complex BaL22(CLO4)2.The crystal structures of the parent macrocyclic complex, 1>2(2-) 1/c (no. 14), a = 11.755(7), b = 21.733(17), c = 15.621(15) Angstroem, β = 90.50(7) deg, Z = 4>, and BaL22(CLO4)2 1/c (, no. 14), a = 12.299(15), b = 9.530(15), c = 25.798(32) Angstroem, β = 108.679(9) deg, Z =2> have been determined.

Synthesis and characterization of 5- and 7-donor Schiff base ligands and spectroscopic evidence for tautomerism: A crystal structure showing tautomeric forms within one ligand

Ogutu, Hezron F.O.,Saban, Waheed,Malgas-Enus, Rehana,Luckay, Robert C.

, p. 392 - 402 (2019/03/11)

An improved method for the synthesis of fifteen Schiff base ligands, of which six are novel, are reported. Optimised yields were obtained and the ligands have been fully characterized via several analytical techniques. It was found that tautomeric forms o

Synthesis, characterization and crystal structure of CD(II) complex with potentially heptadentate Schiff base ligand

Ranjineh Khojasteh, Roya,Jalali Matin, Sara

, p. 83 - 87 (2016/07/15)

(Formula presented) The heptadentate N4O3-type Schiff base was derived from the condensation reaction of salicylaldehyde and tris(2-aminoethyl)amine. The heptadentate Schiff base ligand was characterized by elemental analysis, 1

Synthesis, characterization, and antibacterial activities of Cr(III), Co(III), Ni(II), and Mn(III) complexes of heptadentate Schiff base ligand derived from tris(2-aminoethyl)amine

Matin,Khojasteh

, p. 1763 - 1767 (2015/08/25)

This is the first study of the antibacterial activity of heptadentate Schiff base ligand (trensal) and its Cr(III), Co(III), Ni(II), and Mn(III) complexes that have been synthesized from the heptadentate Schiff base ligand derived from salicylaldehyde and

A cap-type Schiff base acting as a fluorescence sensor for zinc(ii) and a colorimetric sensor for iron(ii), copper(ii), and zinc(ii) in aqueous media

Kim, Kyung Beom,Kim, Hyun,Song, Eun Joo,Kim, Sumi,Noh, Insup,Kim, Cheal

, p. 16569 - 16577 (2013/12/04)

A simple and low cost chemosensor is described. This sensor could simultaneously detect three biologically important metal ions through fluorogenic (Zn2+) and chromogenic (Fe2+, Cu2+, and Zn2+) methods in aqueou

Encapsulating ruthenium and osmium with tris(2-aminoethyl)amine based tripodal ligands

Mandal, Soumik,Seth, Dipravath K.,Gupta, Parna

experimental part, p. 167 - 175 (2012/03/13)

The reaction of a series of tripodal ligands, H3L1,2 and L3-6, with [M(PPh3)2Cl2] (M = Ru, Os) affords a family of coordination cage compounds of the type [M IIIL1,2]

Benign routes for the syntheses of polydentate Schiff base and their lanthanide complexes

Habib, Mohammad,Sain, Sushama,Das, Babulal,Chandra, Swapan K.

experimental part, p. 1501 - 1508 (2012/04/23)

Tris-imine septadentate Schiff base ligand has conveniently made in high yield (~95% or more), when tris(2-aminoethyl)araine condensed with salicylaldehyde using 1:3 molar ratio under solvent free conditions. Lanthanide complexes have also synthesised by

Prochelators triggered by hydrogen peroxide provide hexadentate iron coordination to impede oxidative stress

Leed, Marina G.D.,Wolkow, Natalie,Pham, David M.,Daniel, Catherine L.,Dunaief, Joshua L.,Franz, Katherine J.

experimental part, p. 1161 - 1172 (2012/05/04)

Prochelators are agents that have little affinity for metal ions until they undergo a chemical conversion. Three new aryl boronate prochelators are presented that are responsive to hydrogen peroxide to provide hexadentate ligands for chelating metal ions.

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