99405-03-5Relevant articles and documents
TREATMENT OF DISEASES BY EPIGENETIC REGULATION
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Paragraph 0538, (2013/11/05)
The present disclosure provides non-naturally occurring polyphenol compounds that inhibit the bromodomain and extra terminal domain (BET) proteins. The disclosed compositions and methods can be used for treatment and prevention of cancer, including NUT midline carcinoma, Burkitt's Lymphoma, Acute Myelogenous Leukemia, and Multiple Myeloma; autoimmune or inflammatory diseases or conditions, and sepsis.
Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers
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Page/Page column 7; 16, (2010/02/15)
Porphyrin compounds having a surface attachment group coupled thereto at the 5 position are described. The surface attachment group has the formula: wherein R is —CHCH2 or —CCH and Ar is an aromatic group. Methods and intermediates useful for m