99522-44-8

Upstream product

• 3355-31-5 1-chloro-3-phenyl-2-propyne 
• 7388-28-5 sodium 2-hydroxyethoxide 
• 107-21-1 ethylene glycol 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 
• 591-50-4 iodobenzene 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 96388-83-9 2-tetrahydropyranyloxy-1-iodoethane 
• 2170-06-1 1-Phenyl-2-(trimethylsilyl)acetylene 
• 3973-18-0 2-(prop-2-ynyloxy)ethanol 
• 82490-61-7 3-phenyl-2-propyn-1-yl methanesulfonate 
• 58305-05-8 (2-benzoyloxyethyl)oxymethyl chloride 
• 536-74-3 phenylacetylene 
• 67242-58-4 3-phenylethynyl magnesium iodide 

Downstream Products

• 870194-92-6 2,4-Dichloro-1-[2-(3-phenyl-prop-2-ynyloxy)-ethoxy]-benzene 
• 119476-25-4 (2,5-dihydrofuran-3-yl)(phenyl)methanone 
• 1047643-60-6 (3-chloro-4-{4-[2-(2,4-dichloro-phenoxy)-ethoxymethyl]-5-phenyl-isoxazol-3-yl}-phenyl)-acetic acid methyl ester 
• 514791-84-5 2-[(3-phenylprop-2-yn-1-yl)oxy]acetaldehyde 
• 193091-57-5 2-iodoethyl 3-phenylpropynyl ether 

Relevant academic research and scientific papers

Palladium-Catalyzed Synthesis of Tricyclic Indoles via a N-S Bond Cleavage Strategy

In palladium/norbornene (Pd/NBE) chemistry, the "ortho effect"has been proven to be a key factor in the process of β-carbon elimination to extrude NBE. Herein, we found that the o-iodoaniline protected by a p-methoxybenzenesulfonyl group can recover the "

Catalytic Alkynylation of Cyclic Acetals and Ketals Enabled by Synergistic Gold(I)/Trimethylsilyl Catalysis

A completely regioselective and challenging gold(I)-catalyzed ring-opening of cyclic 1,3-dioxolanes and dioxanes by trimethylsilyl alkynes to set diol-derived propargyl trimethylsilyl bis-ethers is reported. This unprecedented and not trivial transformation does not operate with the catalytic methodologies recently reported for catalytic alkynylation of acyclic acetals/ketals, and is uniquely enabled by the application of a recently introduced synergistic gold(I)-silicon catalysis concept capable of producing simultaneously catalytic amounts of two key players, a silicon-based Lewis superacid and a nucleophilic gold acetylide.

Triflic Acid-Catalyzed Enynes Cyclization: A New Strategy beyond Electrophilic π-Activation

The cyclization of enynes, catalyzed by a transition metal, represents a powerful tool to construct an array of cyclic compounds through electrophilic π-activation. In this paper, we disclose a new and efficient strategy for enynes cyclization catalyzed b

Indium(III)-catalyzed coupling between alkynes and aldehydes to α,β-unsaturated ketones

The combined use of a catalytic amount of InX3 (X = OTf and NTf2) and 1-butanol was found to be effective in formal alkynealdehyde metathesis. With this catalytic system, aromatic alkynes reacted with aromatic aldehydes to give chalcones in moderate to good yields. Alkynals were efficiently converted into 5- to 7-membered cyclic compounds by intramolecular alkyne-aldehyde coupling.

COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families, particularly the activity of PPAR .

Remarkable template effect of a Lewis acid receptor in the intramolecular radical cyclization: Control of reaction pathway as well as stereochemistry

A remarkable template effect in the intramolecular radical cyclization process has been observed by the successful utilization of Lewis acid receptor, aluminum tris(2,6-diphenylphenoxide) (ATPH). The origin of this efficient template effect by ATPH would

Novel pesticides, preparation and use

The specification describes and claims methods of controlling acarine pests by application of a compound of Formula (I), methods of controlling arthropod pests by application of a compound of Formula (IA), compounds of Formula (IA) per se, pesticidal compositions comprising a compound of Formula (IA), and processes for preparing a compound of Formula (IA).

FREE RADICAL REARRANGEMENTS OF ORGANOCOBALOXIMES: ALKYNYL TO CYCLOALKYLIDENE AND HEXENYL TO CYCLOPENTYLMETHYL

Under irradiation by tungsten light in pyridine solution, several substituted alkylcobaloximes undergo rearrangement to more stable substituted alkyl- or alkenyl-cobaloximes.When the same reactions are carried out in the presence of carbon tetrachloride or chloroform, no rearranged organobaloximes are obtained, but a variety of organic products are obtained derived from the interception of transient organic radicals by the halogenated solvent.The rearrangements are rationalised in terms of a reversible homolysis of the carbon-cobalt bond, rearrangement of the organic radical and recapture by the cobalt(II) fragment to give complexes that are more stable to irradiation than their precursors.