99585-12-3

Basic information

• Product Name: 4-CHLORO-2-METHYL-BENZOIC ACID METHYL ESTER
• Synonyms: 4-CHLORO-2-METHYL-BENZOIC ACID METHYL ESTER;Benzoic acid, 4-chloro-2-Methyl-, Methyl ester;Methyl 4-chloro-2-methylbenzoate
• CAS NO: 99585-12-3
• Molecular Formula: C₉H₉ClO₂
• Molecular Weight: 184.62
• EINECS: 604-604-1
• Mol File: 99585-12-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 16 °C
• Boiling Point: 235.9±20.0 °C(Predicted)
• Appearance: /
• Density: 1.186±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-CHLORO-2-METHYL-BENZOIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-2-METHYL-BENZOIC ACID METHYL ESTER(99585-12-3)
• EPA Substance Registry System: 4-CHLORO-2-METHYL-BENZOIC ACID METHYL ESTER(99585-12-3)

Safety Data

• Hazardous Substances Data: 99585-12-3(Hazardous Substances Data)

Usage

Uses

4-Chloro-2-methyl-benzoic acid methyl ester is a useful chemical for the preparation of urea and pyrazole compounds as α7 Nicotinic acetylcholine receptor agonist for the treatment of cognitive impairment.

Upstream product

• 67-56-1 methanol 
• 40137-29-9 2-methyl-4-chlorobenzaldehyde 
• 7499-07-2 4-chloro-2-methylbenzoic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 145908-29-8 methyl 2-(bromomethyl)-4-chlorobenzoate 
• 1040720-97-5 N-[5-(4-chloro-2-methylphenyl)-2H-pyrazol-3-yl]-4-pyrrolidin-1-ylbutyramide 
• 1040721-09-2 N-[5-(4-chloro-2-methylphenyl)-2H-pyrazol-3-yl]-4-piperidin-1-ylbutyramide formate salt 
• 1608129-76-5 5-amino-3-(4-chloro-2-methylphenyl)pyrazole-1-carboxylic acid tert-butyl ester 
• 1608129-65-2 4-pyrrolidin-1-yl-piperidine-1-carboxylic acid [5-(4-chloro-2-methylphenyl)-2H-pyrazol-3-yl]amide 
• 1608129-80-1 C₁₉H₂₂ClN₃O₄ 
• 1040724-41-1 5-(4-chloro-2-methylphenyl)-2H-pyrazol-3-ylamine 
• 73206-63-0 (4-isobutyl-2-methylphenyl)methanol 

Relevant articles and documents

N-Heterocyclic carbene catalyzed esterification of aromatic aldehydes with alcohols under aerobic conditions

A simple, organocatalytic procedure for the direct oxidative esterification of a variety of aromatic aldehydes with alcohols has been described that affords the corresponding aromatic esters in high yields. The method employs N-heterocyclic carbenes as catalysts and molecular O2 as an oxidant under ambient conditions.

Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions

The inventions disclosed herein relate to the discovery of the use of compounds having the formula shown below and certain subgenera or species thereof, as flavor or taste modifiers, particularly, savory (“umami”) taste modifiers, savory flavoring agents