99768-21-5

Basic information

• Product Name: 4-BroMo-1-Methanesulfonyl-2-Methylbenzene
• Synonyms: 4-BroMo-1-Methanesulfonyl-2-Methylbenzene;4-bromo-2-methyl-1-(methylsulfonyl)benzene
• CAS NO: 99768-21-5
• Molecular Formula: C₈H₉BrO₂S
• Molecular Weight: 249.12486
• Mol File: 99768-21-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform, DMSO (Slightly)
• CAS DataBase Reference: 4-BroMo-1-Methanesulfonyl-2-Methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BroMo-1-Methanesulfonyl-2-Methylbenzene(99768-21-5)
• EPA Substance Registry System: 4-BroMo-1-Methanesulfonyl-2-Methylbenzene(99768-21-5)

Safety Data

• Hazardous Substances Data: 99768-21-5(Hazardous Substances Data)

Usage

General Description

4-Bromo-1-methanesulfonyl-2-methylbenzene, also known as p-tolylsulfonyl bromide, is a chemical compound with the molecular formula C8H9BrO2S. It is a colorless to pale yellow liquid that is a versatile building block in organic synthesis. 4-Bromo-1-methanesulfonyl-2-methylbenzene is widely used in pharmaceutical and agrochemical industries for the synthesis of various compounds. It is also employed as a reagent in the preparation of sulfonyl-based compounds and is an important intermediate in the production of active pharmaceutical ingredients. The compound has a wide range of applications due to its unique reactivity and functional group compatibility, making it a valuable tool for researchers and synthetic chemists.

Upstream product

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Downstream Products

• 1104450-19-2 1-(3-methyl-4-(methylsulfonyl)phenyl)-4-(1-(5-propylpyrimidin-2-yl)piperidin-4-yloxy)pyridin-2(1H)-one 

Relevant articles and documents

SUBSTITUTED QUINOLINES AND THEIR USE AS MEDICAMENTS

The invention relates to new substituted quinolines of formula (1) wherein R1 is a linear or branched C1-6-alkyl, wherein R1 may optionally be substituted by R3 which is selected from the group consisting of a three-, four-, five-, six- or seven-membered cycloalkl; a five-, six- or seven-membered, saturated heterocycle comprising one, two or three heteroatoms each independently selected from the group consisting of N, S and O; and a five- or six-membered heteroaryl comprising one, two or three heteroatoms each independently selected from the group consisting of N, S and O; wherein R3 may optionally be substituted further substituted as defined in claim 1 and wherein R2 is selected from the group consisting of halogen, phenyl, a five- or six-membered monocyclic heteroaryl comprising one, two or three heteroatoms each independently selected from the group consisting of N, S and O; a bicyclic, nine-, ten- or eleven-membered, either aromatic or non-aromatic, but not fully saturated heterocycle comprising one, two, three or four heteroatoms each independently selected from the group consisting of N, S and O; wherein R2 may optionally be further substituted as defined in claim 1, and their use in the preparation of medicaments for the treatment of disease such as asthma, COPD, allergic rhinitis, allergic dermatitis and rheumatoid arthritis.

PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS

Novel compounds are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR 119 G protein-coupled receptor modulator therapy. These novel compounds have the structure Formula I or Formula IA.