99768-21-5

Usage

Uses

Used in Pharmaceutical Industry:
4-Bromo-1-methanesulfonyl-2-methylbenzene is used as a key intermediate for the synthesis of various compounds in the pharmaceutical industry. Its unique reactivity and functional group compatibility make it an essential component in the development of active pharmaceutical ingredients.
Used in Agrochemical Industry:
In the agrochemical industry, 4-Bromo-1-methanesulfonyl-2-methylbenzene is utilized as a building block for the synthesis of various compounds. Its versatility and reactivity contribute to the creation of effective agrochemical products.
Used as a Reagent in Sulfonyl-based Compounds Preparation:
4-Bromo-1-methanesulfonyl-2-methylbenzene serves as a reagent in the preparation of sulfonyl-based compounds. Its properties allow for the efficient synthesis of these compounds, which have a wide range of applications in various industries.
Overall, 4-Bromo-1-methanesulfonyl-2-methylbenzene is a crucial chemical compound with diverse applications in different industries, primarily due to its unique reactivity and functional group compatibility.

Upstream product

• 89981-03-3 methyl 4-bromo-2-methylphenyl sulphide 
• 14092-00-3 methyl o-tolyl sulfide 
• 139937-37-4 5-bromo-2-toluenesulfonyl chloride 
• 79-08-3 bromoacetic acid 
• 116632-39-4 2-methyl-4-bromoiodobenzene 
• 20277-69-4 sodium methansulfinate 

Downstream Products

• 1104450-19-2 1-(3-methyl-4-(methylsulfonyl)phenyl)-4-(1-(5-propylpyrimidin-2-yl)piperidin-4-yloxy)pyridin-2(1H)-one 

Relevant academic research and scientific papers

SUBSTITUTED QUINOLINES AND THEIR USE AS MEDICAMENTS

The invention relates to new substituted quinolines of formula (1) wherein R1 is a linear or branched C1-6-alkyl, wherein R1 may optionally be substituted by R3 which is selected from the group consisting of a three-, four-, five-, six- or seven-membered cycloalkl; a five-, six- or seven-membered, saturated heterocycle comprising one, two or three heteroatoms each independently selected from the group consisting of N, S and O; and a five- or six-membered heteroaryl comprising one, two or three heteroatoms each independently selected from the group consisting of N, S and O; wherein R3 may optionally be substituted further substituted as defined in claim 1 and wherein R2 is selected from the group consisting of halogen, phenyl, a five- or six-membered monocyclic heteroaryl comprising one, two or three heteroatoms each independently selected from the group consisting of N, S and O; a bicyclic, nine-, ten- or eleven-membered, either aromatic or non-aromatic, but not fully saturated heterocycle comprising one, two, three or four heteroatoms each independently selected from the group consisting of N, S and O; wherein R2 may optionally be further substituted as defined in claim 1, and their use in the preparation of medicaments for the treatment of disease such as asthma, COPD, allergic rhinitis, allergic dermatitis and rheumatoid arthritis.

Substituted Quinolines and Their Use As Medicaments

Disclosed are substituted quinolines of formula 1 wherein R1 and R2 are defined herein, the processing of making and using the same.

PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS

Novel compounds are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR 119 G protein-coupled receptor modulator therapy. These novel compounds have the structure Formula I or Formula IA.