99875-16-8

Upstream product

• 842-74-0 4-benzylidene-2-phenyloxazole-5(4H)-one 
• 56-40-6 glycine 
• 17606-70-1 (4Z)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one 
• 99875-12-4 {[(2Z)-2-benzamido-3-phenylprop-2-enoyl]amino}acetic acid 
• 99875-10-2 N-n-butyl-2-benzoylaminocinnamide 
• 62-53-3 aniline 
• 59698-95-2 (4-benzylidene-5-oxo-2-phenyl-4,5-dihydro-imidazol-1-yl)-acetic acid ethyl ester 

Downstream Products

• 213838-76-7 4-benzylidene-2-phenyl-5-imidazolone-acetyl chloride 
• 213839-09-9 {5-Oxo-2-phenyl-4-[1-phenyl-meth-(Z)-ylidene]-4,5-dihydro-imidazol-1-yl}-acetyl isothiocyanate 
• 213838-77-8 4-benzylidene-2-phenyl-5-imidazolone-acetic acid azide 
• 213838-86-9 Benzoic acid N'-(2-{5-oxo-2-phenyl-4-[1-phenyl-meth-(Z)-ylidene]-4,5-dihydro-imidazol-1-yl}-acetyl)-hydrazide 
• 213838-87-0 4-Nitro-benzoic acid N'-(2-{5-oxo-2-phenyl-4-[1-phenyl-meth-(Z)-ylidene]-4,5-dihydro-imidazol-1-yl}-acetyl)-hydrazide 

Relevant academic research and scientific papers

Synthesis and Anticholinesterase Activity of [(4Z)-2-Aryl-4-(arylmethylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl]alkanoic Acids

ω-[(4Z)-2-Aryl-4-arylmethylidene-5-oxo-4,5-dihydro-1H-imidazol-1-yl]alkanoic acids were synthesized by reaction of N-substituted α,β-dehydropeptides with chloro(trimethyl)silane or 1,1,1,3,3,3-hexamethyldisilazane. Both initial peptides and (4H)-imidazol-

Synthesis and biological activity of certain 1-substituted-4-benzylidene-2-phenyl-5-imidazolones

1-Substituted-4-ben2ylidene-2-phenyl-5-imidazolone derivatives 4-7, 9-15 have been synthesised for their potential biological activity. The synthesis involves the base and acid catalyzed reactions of azide 3 and/or acid chloride 2. Compounds 5c and 5d are easily cyclized to give 1,3,4-oxadiazole derivatives 6a and 6b. Representative examples of internal Friedel-Craft and [4+2]cycloaddition have also been investigated.

Cyclisation of N-Substituted 2-Acylamino-2-alkenamides: Some Observations

2-Acetylaminocinnamanilide undergoes cyclisation to afford 3a in neutral, acidic and basic media.However, N-substituted 2-benzoylamino-3-aryl-2-alkenamides (2b-f) afford the corresponding 5-imidazolones (3b-f) only under neutral or acidic condition.Compou