99934-01-7Relevant academic research and scientific papers
Several approaches to cyanide ion-catalyzed synthesis of 4-aroyl-1-phenyl-1h-pyrazolo[3,4-d]pyrimidines
Miyashita, Akira,Suzuki, Yumiko,Ohta, Kiyono,Iwamoto, Ken-Ichi,Higashino, Takeo
, p. 407 - 414 (2007/10/03)
- 4-Aroyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidines (5) were formed in low yields by reaction of 4-chloro-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (4) with arenecarbaldehydes (3) in the presence of potassium cyanide. Similar reaction of 4-tosyl-1-phenyl-1H-pyra
Catalytic action of azolium salts. IX. Synthesis of 6-aroyl-9H-purines and their analogues by nucleophilic aroylation catalyzed by imidazolium or benzimidazolium salt
Miyashita, Akira,Suzuki, Yumiko,Iwamoto, Ken-Ichi,Higashino, Takeo
, p. 390 - 399 (2007/10/03)
In the presence of 1,3-dimethylimidazolium iodide (1), 6-chloro-9- phenyl-9H-purine (7) and 4-chloro-5,6-dimethylpyrrolo[2,3-d]pyrimidines 40- 42 underwent nucleophilic aroylation with arenecarbaldehydes (5) to give the corresponding fused aroylpyrimidine
Synthesis and reactivities of 1,3-dimethyl-2-(α-hydroxy-benzyl)imidazolium and 1,3-dimethyl-2-(α-hydroxybenzyl)benzimidazolium iodides
Miyashita, Akira,Kurachi, Akihito,Matsuoka, Yoshiyuki,Tanabe, Noriko,Suzuki, Yumiko,Iwamoto, Ken-Ichi,Higashino, Takeo
, p. 417 - 426 (2007/10/03)
1,3-Dimethyl-2-(α-hydroxybenzyl)benzimidazolium iodide (3a) was synthesized from 1-methylbenzimidazole (10) through two steps involving lithiation and quaternization. Treatment of 3a with 4-chloro-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (6) afforded 4-benzoyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (15a). 4-Benzoylquinazoline (14a) and 7-benzoyl-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine (16a) were given by reaction of 3a with 4-chloroquinazoline (5) and 7-chloro-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine (7). Treatment of 3a with benzaldehyde (9a) gave benzoin (8a). Similar results were obtained in the reactions of 1,3-dimethyl-2-(α-hydroxybenzyl)imidazolium iodide (4a).
Triazolo[4,5-d]pyrimidines. X. Halogen-metal exchange reaction of 7-halo-3-phenyl-3H-1,2,3-triazolo[4,5-d)pyrimidines with butyllithium
Tanji,Kato,Higashino
, p. 2793 - 2796 (2007/10/02)
The amino group at the 7-position on the 3H-1,2,3-triazolo[4,5-d]pyrimidine ring was converted into halogen atoms by treatment with isopentyl nitrite in halomethanes, in satisfactory yields. The halogen-metal exchange reaction between 7-iodo-3-phenyl-3H-1
Triazolopyrimidines. VIII. Aryl Migration of 7-Aroyl-3H-1,2,3-triazolopyrimidines to 7-Aryl-3H-1,2,3-triazolopyrimidines
Higashino, Takeo,Takemoto, Masumi,Miyashita, Akira,Hayashi, Eisaku
, p. 1395 - 1399 (2007/10/02)
When mixtures of 7-chloro-3-phenyl-3H-1,2,3-triazolopyrimidine (4), aromatic aldehydes (5), and a catalytic amount of 1,3-dimethylbenzimidazolium iodide were refluxed in tetrahydrofuran (THF) in the presence of sodium hydride, 7-aroyl-3-phenyl-3H-1
