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2-(3-CHLORO-PROPENYL)-1,4-DIFLUORO-BENZENE, also known as (E)-2-(3-Chloro-1-propenyl)-1,4-difluorobenzene, is an organic compound with a unique molecular structure that features a 1,4-difluorobenzene core and a 3-chloro-1-propenyl group. 2-(3-CHLORO-PROPENYL)-1,4-DIFLUORO-BENZENE is characterized by its potential reactivity and versatility in chemical synthesis, making it a valuable intermediate in the development of various pharmaceutical compounds.

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  • 149946-42-9 Structure
  • Basic information

    1. Product Name: 2-(3-CHLORO-PROPENYL)-1,4-DIFLUORO-BENZENE
    2. Synonyms: 2-(3-CHLORO-PROPENYL)-1,4-DIFLUORO-BENZENE;(E)-2-(3-Chloroprop-1-en-1-yl)-1,4-difluorobenzene
    3. CAS NO:149946-42-9
    4. Molecular Formula: C9H7ClF2
    5. Molecular Weight: 188.6016864
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 149946-42-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(3-CHLORO-PROPENYL)-1,4-DIFLUORO-BENZENE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(3-CHLORO-PROPENYL)-1,4-DIFLUORO-BENZENE(149946-42-9)
    11. EPA Substance Registry System: 2-(3-CHLORO-PROPENYL)-1,4-DIFLUORO-BENZENE(149946-42-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 149946-42-9(Hazardous Substances Data)

149946-42-9 Usage

Uses

Used in Pharmaceutical Industry:
2-(3-CHLORO-PROPENYL)-1,4-DIFLUORO-BENZENE is used as a key intermediate for the synthesis of [application type] for [application reason]. Its unique structure allows for the development of various pharmaceutical compounds with different therapeutic applications.
Used in Aldose Reductase Inhibition:
In the pharmaceutical industry, 2-(3-CHLORO-PROPENYL)-1,4-DIFLUORO-BENZENE is used as a starting material for the preparation of phthalazineacetic acid derivatives. These derivatives act as aldose reductase inhibitors, which are important for the treatment of complications associated with diabetes, such as neuropathy and cataracts.
Used in Antimicrobial Applications:
Additionally, 2-(3-CHLORO-PROPENYL)-1,4-DIFLUORO-BENZENE is utilized in the preparation of quinolinones and their analogs. These compounds exhibit antimicrobial properties, making them valuable in the development of new antibiotics to combat drug-resistant bacterial infections.

Check Digit Verification of cas no

The CAS Registry Mumber 149946-42-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,9,4 and 6 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 149946-42:
(8*1)+(7*4)+(6*9)+(5*9)+(4*4)+(3*6)+(2*4)+(1*2)=179
179 % 10 = 9
So 149946-42-9 is a valid CAS Registry Number.

149946-42-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[(E)-3-chloroprop-1-enyl]-1,4-difluorobenzene

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:149946-42-9 SDS

149946-42-9Relevant articles and documents

COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS

-

, (2010/11/25)

The present invention relates to compounds that demonstrate antibacterial activity, processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment of bacterial infections in warm-blooded animals such as humans. In particular this invention relates to compounds useful for the treatment of bacterial infections in warm-blooded animals such as humans, more particularly to the use of these compounds in the manufacture of medicaments for use in the treatment of bacterial infections in warm-blooded animals such as humans.

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