(E)-2-(3-Chloroprop-1-en-1-yl)-1,4-difluorobenzene

Base Information

Chemical Name:(E)-2-(3-Chloroprop-1-en-1-yl)-1,4-difluorobenzene
CAS No.:149946-42-9
Molecular Formula:C9H7ClF2
Molecular Weight:188.604
Hs Code.:
DSSTox Substance ID:DTXSID00469350
Wikidata:Q82297021
Mol file:149946-42-9.mol

Synonyms:149946-42-9;(E)-2-(3-Chloroprop-1-en-1-yl)-1,4-difluorobenzene;2-[(E)-3-chloroprop-1-enyl]-1,4-difluorobenzene;Benzene, 2-[(1E)-3-chloro-1-propen-1-yl]-1,4-difluoro-;SCHEMBL704659;SCHEMBL704660;(E)-2-(3-Chloro-1-propenyl)-1,4-difluorobenzene;DTXSID00469350;BQORONBSXKWTEZ-OWOJBTEDSA-N;ZFA94642;MFCD14706382;WS-00232;CS-0334034;2-(3-chloroprop-1-enyl)-1,4-difluorobenzene;2-[(1E)-3-chloro-1-propenyl]-1,4-difluorobenzene;2-[(1E)-3-chloroprop-1-en-1-yl]-1,4-difluorobenzene

Suppliers and Price of (E)-2-(3-Chloroprop-1-en-1-yl)-1,4-difluorobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(3-Chloro-propenyl)-1,4-difluoro-benzene
500mg
$ 330.00

Matrix Scientific
(E)-2-(3-Chloroprop-1-en-1-yl)-1,4-difluorobenzene 95+%
250mg
$ 742.00

Matrix Scientific
(E)-2-(3-Chloroprop-1-en-1-yl)-1,4-difluorobenzene 95+%
1g
$ 1647.00

American Custom Chemicals Corporation
(E)-2-(3-CHLOROPROP-1-EN-1-YL)-1,4-DIFLUOROBENZENE 95.00%
1G
$ 1183.35

American Custom Chemicals Corporation
(E)-2-(3-CHLOROPROP-1-EN-1-YL)-1,4-DIFLUOROBENZENE 95.00%
5MG
$ 505.88

Alichem
(E)-2-(3-Chloroprop-1-en-1-yl)-1,4-difluorobenzene
1g
$ 464.10

AK Scientific
(E)-2-(3-Chloroprop-1-en-1-yl)-1,4-difluorobenzene
1g
$ 2273.00

AK Scientific
(E)-2-(3-Chloroprop-1-en-1-yl)-1,4-difluorobenzene
250mg
$ 1051.00

Total 5 raw suppliers

Chemical Property of (E)-2-(3-Chloroprop-1-en-1-yl)-1,4-difluorobenzene

Chemical Property:

PSA：0.00000
LogP:3.21680
Storage Temp.:2-8°C
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:188.0204342
Heavy Atom Count:12
Complexity:159

Purity/Quality:

99% ^*data from raw suppliers

2-(3-Chloro-propenyl)-1,4-difluoro-benzene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)C=CCCl)F
Isomeric SMILES:C1=CC(=C(C=C1F)/C=C/CCl)F
Uses (E)-2-(3-Chloro-1-propenyl)-1,4-difluorobenzene can be useful in the preparation of phthalazineacetic acid derivative as aldose reductase inhibitor. It may also be useful in the preparation of quinolinones and analogs as antimicrobials.

Technology Process of (E)-2-(3-Chloroprop-1-en-1-yl)-1,4-difluorobenzene

There total 2 articles about (E)-2-(3-Chloroprop-1-en-1-yl)-1,4-difluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 767355-26-0
trans-3-(2,5-difluoro-phenyl)-prop-2-en-1-ol

: 149946-42-9
2-[(1E)-3-chloroprop-1-en-1-yl]-1,4-difluorobenzene

Guidance literature:: trans-3-(2,5-difluoro-phenyl)-prop-2-en-1-ol; With hydrogenchloride; In 1,4-dioxane; water; at 100 ℃; for 3h; Microwave irradiation;

With sodium hydrogencarbonate; In water; ethyl acetate;

Reference yield:

: 112898-33-6
3-(2,5-difluorophenyl)acrylic acid

: 149946-42-9
2-[(1E)-3-chloroprop-1-en-1-yl]-1,4-difluorobenzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine; isobutyl chloroformate / tetrahydrofuran / 0.5 h / 20 °C

1.2: 1 h / 0 - 20 °C

1.3: 0 °C / pH 7

2.1: hydrogenchloride / 1,4-dioxane; water / 3 h / 100 °C / Microwave irradiation

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; isobutyl chloroformate; In tetrahydrofuran; 1,4-dioxane; water;