767355-26-0Relevant articles and documents
Solid-phase synthesis and biological evaluation of piperazine-based novel bacterial topoisomerase inhibitors
Flagstad, Thomas,Pedersen, Mette T.,Jakobsen, Tim H.,Felding, Jakob,Tolker-Nielsen, Tim,Givskov, Michael,Qvortrup, Katrine,Nielsen, Thomas E.
supporting information, (2021/12/24)
There is an emerging global need for new and more effective antibiotics against multi-resistant bacteria. This situation has led to massive industrial investigations on novel bacterial topoisomerase inhibitors (NBTIs) that target the vital bacterial enzym
4-(1-AMINO-ETHYL)-CYCLOHEXYLAMINE DERIVATIVES
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Page/Page column 25, (2010/03/02)
The invention relates to compounds of formula (I) wherein R0 represents H or OH; R1 represents alkoxy; U and W represent N, V represents CH and R2 represents H or F, or U and V represent CH, W represents N and R2 /su
TRICYCLIC NITROGEN CONTAINING COMPOUNDS AND THEIR USE AS ANTIBACTERIALS
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, (2009/12/27)
Compounds of Formula (I) or a pharmaceutically acceptable salt or N-oxide thereof; Formula (I) (relative stereochemistry shown) wherein: Z1, Z2 , L are as defined, U represents a cyclic group selected from: phenyl, pyridyl, pyridazin
TRICYCLIC COMPOUNDS AS ANTIBACTERIALS
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, (2008/12/08)
Tricyclic nitrogen containing compounds of formula (I) and their use as antibacterials.
4-(1-AMINO-ETHYL)-CYCLOHEXYLAMINE DERIVATIVES
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Page/Page column 61, (2008/12/06)
The invention relates to compounds of formula (I) wherein R0 represents H or OH; R1 represents alkoxy; U and W represent N, V represents CH and R2 represents H or F, or U and V represent CH, W represents N and R2/sup
3-AMINO-6-(1-AMINO-ETHYL)-TETRAHYDROPYRAN DERIVATIVES
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Page/Page column 40, (2009/01/24)
The invention relates to antibacterial compounds of formula I wherein R1 represents halogen or alkoxy; U and W each represent N, V represents CH and R2 represents H or F, or U and V each represent CH, W represents N and R2
ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES
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Page/Page column 41-42, (2008/06/13)
The invention relates to antibiotic ethanol or 1,2-ethanediol cyclohexyl derivatives of formula (I) wherein R1 represents (C1-C4)alkoxy; one or two of U, V, W and X represent(s) N and the remaining represent each independently CH or, in the case of V or X
New Piperidine Antibiotics
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Page/Page column 27, (2010/11/28)
The invention relates to novel, antibacterially active piperidine derivatives of the formula wherein one of U and V represents N, the other represents N or CH; M represents CH2CH2, CH═CH, CH(OH)CH(OH), CH(OH)CH2, CH(NHsub
TETRAHYDROPYRANE ANTIBIOTICS
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Page/Page column 74, (2010/11/28)
The invention relates to antibiotic tetrahydro rane derivatives of formula (I).
ANTIBIOTIC COMPOUNDS
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Page/Page column 25, (2010/11/28)
The invention relates to selected antibiotics of formula (Al) wherein R1 represents alkyl, alkoxy, haloalkoxy, halogen or cyano; one or two of U, V, W and X represent(s) N, the remaining represent CH, or, in case of U, V and/or W, may also repr