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189102-97-4

5,6-Dichloro-3H-imidazo[4,5-b]pyridine, also known as DCIP, is a heterocyclic organic compound with the molecular formula C7H4Cl2N2. It is commonly used as a reagent in chemical and biological research due to its ability to act as a potent inhibitor of protein kinase C, a crucial enzyme involved in various cell signaling pathways. DCIP's unique structure and biological activities make it a valuable tool for studying cellular processes and for the development of new therapeutic agents.

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  • 189102-97-4 Structure

  • Basic information

    1. Product Name: 5,6-dichloro-3H-iMidazo[4,5-b]pyridine
    2. Synonyms: 5,6-dichloro-3H-iMidazo[4,5-b]pyridine
    3. CAS NO:189102-97-4
    4. Molecular Formula: C6H3Cl2N3
    5. Molecular Weight: 188.01412
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 189102-97-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 204.3±50.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.79±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. PKA: 6.17±0.40(Predicted)
    10. CAS DataBase Reference: 5,6-dichloro-3H-iMidazo[4,5-b]pyridine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 5,6-dichloro-3H-iMidazo[4,5-b]pyridine(189102-97-4)
    12. EPA Substance Registry System: 5,6-dichloro-3H-iMidazo[4,5-b]pyridine(189102-97-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 189102-97-4(Hazardous Substances Data)

189102-97-4 Usage

Uses

Used in Pharmaceutical Research:
5,6-Dichloro-3H-imidazo[4,5-b]pyridine is used as a research compound for its potential antitumor and antiviral activities, making it a significant target for pharmaceutical research.
Used in Chemical and Biological Research:
5,6-Dichloro-3H-imidazo[4,5-b]pyridine is used as a reagent in chemical and biological research for studying cellular processes and the development of new therapeutic agents, due to its ability to act as a potent inhibitor of protein kinase C.

Check Digit Verification of cas no

The CAS Registry Mumber 189102-97-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,1,0 and 2 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 189102-97:
(8*1)+(7*8)+(6*9)+(5*1)+(4*0)+(3*2)+(2*9)+(1*7)=154
154 % 10 = 4
So 189102-97-4 is a valid CAS Registry Number.

189102-97-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5,6-Dichloro-1H-imidazo[4,5-b]pyridine

1.2 Other means of identification

Product number -
Other names 5,6-Dichloro-3H-imidazo[4,5-b]pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:189102-97-4 SDS

189102-97-4Downstream Products

189102-97-4Relevant articles and documents

3-[3'-hydroxymethyl)-4'-hydroxybutyl]imidazo[4,5-b]pyridines - Novel antiviral agents

Cundy, Darren J.,Holan, George,Otaegui, Michelle,Simpson, Gregory W.

, p. 669 - 674 (1997)

Derivatives of 3- and 1-(4'-hydroxy-3'-(hydroxymethyl)butyl)-imidazo[4,5-b]pyridine were prepared in several steps from 2-amino-5-chloropyridine. Selected compounds were evaluated against human cytomegalovirus (HCMV), herpes simplex viruses (HSV1/HSV2) and varicella tester virus (VZV). Details of their synthesis and biological activities are presented.

Azabenzimidazole derivative having AMPK-activating activity

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Page/Page column 34, (2017/03/08)

Disclosed is a compound which is useful as an AMPK activator. A compound represented by formula: or a pharmaceutically acceptable salt thereof, wherein R4 is hydrogen, or substituted or unsubstituted alkyl, R1, R2 and R3 are each independently hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl or the like, with the proviso that R1, R2 and R3 are not simultaneously hydrogen, X is a single bond, —S—, —O—, —NR5—, —C(═O)— or the like, R5 is hydrogen, or substituted or unsubstituted alkyl, Y is substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted heterocyclyl or the like.

HETERO RING-FUSED IMIDAZOLE DERIVATIVE HAVING AMPK ACTIVATING EFFECT

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Paragraph 0621; 0626; 0627, (2013/07/25)

Disclosed is a compound which is useful as an AMPK activator. A compound represented by the formula: its pharmaceutically acceptable salt, or a solvate thereof, wherein a group represented by the formula: is a group represented by the formula: R1 /s

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