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1-(5-Chloro-1H-indazol-1-yl)ethanone is a chemical compound with the formula C9H7ClN2O. It is an indazole derivative that contains a chlorine atom and an ethanone group. This yellow solid is commonly used in organic synthesis and pharmaceutical research, serving as a potential intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable tool for scientists and researchers in the field of organic chemistry, with potential applications in the development of new pharmaceuticals and biologically active molecules.

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  • 98083-43-3 Structure
  • Basic information

    1. Product Name: 1-(5-Chloro-1H-indazol-1-yl)ethanone
    2. Synonyms: 1-(5-Chloro-1H-indazol-1-yl)ethanone;1-(5-Chloro-1H-indazol-1-yl)
    3. CAS NO:98083-43-3
    4. Molecular Formula: C9H7ClN2O
    5. Molecular Weight: 194.61768
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 98083-43-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 342.7±34.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.37±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: -2.85±0.30(Predicted)
    10. CAS DataBase Reference: 1-(5-Chloro-1H-indazol-1-yl)ethanone(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1-(5-Chloro-1H-indazol-1-yl)ethanone(98083-43-3)
    12. EPA Substance Registry System: 1-(5-Chloro-1H-indazol-1-yl)ethanone(98083-43-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 98083-43-3(Hazardous Substances Data)

98083-43-3 Usage

Uses

Used in Pharmaceutical Research:
1-(5-Chloro-1H-indazol-1-yl)ethanone is used as a research compound for the development of new pharmaceuticals, leveraging its chemical properties to create novel therapeutic agents.
Used in Organic Synthesis:
In the field of organic chemistry, 1-(5-Chloro-1H-indazol-1-yl)ethanone is used as a building block for the production of other chemicals, contributing to the synthesis of complex organic molecules.
Used in the Development of Biologically Active Molecules:
1-(5-Chloro-1H-indazol-1-yl)ethanone is utilized as a precursor in the creation of biologically active molecules, potentially leading to advancements in medicine and healthcare.

Check Digit Verification of cas no

The CAS Registry Mumber 98083-43-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,0,8 and 3 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 98083-43:
(7*9)+(6*8)+(5*0)+(4*8)+(3*3)+(2*4)+(1*3)=163
163 % 10 = 3
So 98083-43-3 is a valid CAS Registry Number.

98083-43-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(5-Chloro-1H-indazol-1-yl)ethanone

1.2 Other means of identification

Product number -
Other names 1-(5-chloroindazol-1-yl)ethanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:98083-43-3 SDS

98083-43-3Downstream Products

98083-43-3Relevant articles and documents

Conjugate base catalysed one-pot synthesis of pyrazoles from β-formyl enamides

Saikia, Anil,Barthakur, Madan G.,Borthakur, Moyurima,Saikia, Chandan J.,Bora, Utpal,Boruah, Romesh C.

, p. 43 - 46 (2006)

A novel one-pot synthesis of pyrazoles has been accomplished by the reaction of β-formyl enamides with hydroxylamine hydrochloride catalysed by potassium dihydrogenphosphate in acid medium.

Azoles. Part 14: On the behaviour of 5-chloro-2-nitroindazole against aliphatic and cyclic amines

Wrzeciono,Dudzinska-Usarewicz,Majewska,et al.

, p. 105 - 108 (2007/10/02)

The authors describe the synthesis of 5-chloro-1- (7) and 5-chloro-2-nitroindazole (5). 5 reacts with methyl, dimethyl and diethyl amine, pyrrolidine, piperidine and morpholine to form besides 5-chloro-3-nitroindazole (6) and 8 the corresponding 3-amino-5-chloroindazoles 9-12. The isomerization of 5 to 6 takes place under the influence of light and temperature too.

Aromatic Diazonium Salts, X. - A One-Pot Procedure for the Jacobson Synthesis of Indazole

Ruechardt, Christoph,Hassmann, Volker

, p. 908 - 927 (2007/10/02)

Procedures are described for a one-pot synthesis of 1H-indazole and substituted indazoles 3 in good yield (Table 1) from o-toluidines 2, alkyl nitrite or nitrous oxides, potassium acetate, and acetic anhydride in benzene.The spectroscopic properties of substituted indazoles (Tables 2-4) are discussed. - 4-Phenylcinnoline (18) is prepared by the same procedure from o-(α-methylenebenzyl)aniline.

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