Ethanol, 2-bromo-

The 2-Bromoethanol, with the CAS registry number 540-51-2, is also known as Ethylene bromohydrin. It belongs to the product categories of Pharmaceutical Intermediates; Omega-Bromoalkanols; Omega-Functional Alkanols, Carboxylic Acids, Amines & Halides; ASTM 5578: Analysis of Ethylene Oxide in AirAlphabetic; A-BMethod Specific; Alpha Sort; ASTM Air Monitoring; B; BI - BZChemical Class; Bromo; Halogenated; Volatiles/ Semivolatiles. Its EINECS registry number is 208-748-1. This chemical's molecular formula is C₂H₅BrO and molecular weight is 124.96. What's more, its IUPAC name is the same with its product name. It should be stored in a cool, dry and well-ventilated place.

Physical properties about 2-Bromoethanol are: (1)ACD/LogP: 0.263; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.26; (4)ACD/LogD (pH 7.4): 0.26; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 33.12; (8)ACD/KOC (pH 7.4): 33.12; (9)#H bond acceptors: 1; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 20.23 Å²; (13)Index of Refraction: 1.482; (14)Molar Refractivity: 20.581 cm³; (15)Molar Volume: 72.237 cm³; (16)Polarizability: 8.159×10^-24cm³; (17)Surface Tension: 39.06 dyne/cm; (18)Density: 1.73 g/cm³; (19)Flash Point: 57.134 °C; (20)Enthalpy of Vaporization: 43.53 kJ/mol; (21)Boiling Point: 136.21 °C at 760 mmHg; (22)Vapour Pressure: 3.178 mmHg at 25 °C.

Preparation of 2-Bromoethanol: this chemical can be prepared by ethane-1,2-diol. The reaction occurs with reagent HBr and other condition of heating for 8 hours. The yield is 49 %.

Uses of 2-Bromoethanol: (1) it is used as a solvent and organic synthetic raw material; (2) it is used to produce other chemicals. For example, it can react with piperidine to get 2-piperidin-1-yl-ethanol. This reaction needs reagent benzene at temperature of 80 °C. The reaction time is 72 hours. The yield is 85 %.

When you are dealing with this chemical, you should be very careful. This chemical may cause damage to health at low levels and it may cause inflammation to the skin or other mucous membranes. It is harmful by inhalation, in contact with skin and if swallowed. In addition, it is toxic by inhalation, in contact with skin and if swallowed. Therefore, you should wear suitable protective clothing, gloves and eye/face protection. In case of contacting with eyes, you should rinse immediately with plenty of water and seek medical advice. And in case of accident or if you feel unwell you should seek medical advice immediately.

You can still convert the following datas into molecular structure:
(1) SMILES: BrCCO
(2) InChI: InChI=1S/C2H5BrO/c3-1-2-4/h4H,1-2H2
(3) InChIKey: LDLCZOVUSADOIV-UHFFFAOYSA-N

The toxicity data is as follows: