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Basic information

  • Name:
  • 5-Methoxytryptamine

  • CAS No.:
  • 608-07-1

  • Molecular Structure:
  • Formula:
  • C11H14N2O
  • Molecular Weight:
  • 190.27
  • Synonyms:
  • Indole,3-(2-aminoethyl)-5-methoxy- (6CI,8CI);2-(5-Methoxyindol-3-yl)ethylamine;2-[5-(Methyloxy)-1H-indol-3-yl]ethanamine;3-(2-Aminoethyl)-5-methoxyindole;5-MOT;5-Methoxy-1H-indole-3-ethanamine;Deacetylmelatonin;Methoxytryptamine;NSC 56422;[2-(5-Methoxy-1H-indol-3-yl)ethyl]amine;
  • EINECS:
  • 210-153-7
  • Melting Point:
  • 245-250 °C (dec.)(lit.)
  • Appearance:
  • White to tan crystalline powder
  • Hazard Symbols:
  • HarmfulXn
  • Risk Codes:
  • 22-36/37/38-20/21/22
  • Safety Description:
  • 36-26 Details

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Chemistry

Molecular Structure:

Molecular Formula: C11H10NO3
Molecular Weight: 204.202
IUPAC Name: 2-(5-Methoxy-1H-indol-3-yl)ethanamine
Synonyms of 5-Methoxytryptamine (CAS NO.608-07-1): 3-(2-Aminoethyl)-5-methoxyindole ; 5-22-12-00018 (Beilstein Handbook Reference) ; 5-Mot ; 5MOT ; BRN 0145587 ; EINECS 210-153-7 ; Meksamin (free base) ; Methoxytryptamine ; Mexamine ; Mexamine base ; NSC 56422 ; 1H-Indole-3-ethanamine, 5-methoxy- (9CI) ; 2-(5-Methoxyindol-3-yl)ethylamine ; Indole, 3-(2-aminoethyl)-5-methoxy-
CAS NO: 608-07-1
Classification Code: Drug / Therapeutic Agent ; Mutation data ; Reproductive Effect
Melting point: 245-250 °C 
Storage temp.: 2-8°C
Form: crystalline
Color: white
Merck: 13,6032

Uses

 5-Methoxytryptamine (CAS NO.608-07-1) is used as intermediates in organic synthesis.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 176mg/kg (176mg/kg)   Journal of Toxicology and Environmental Health. Vol. 1, Pg. 515, 1976.
mouse LD50 intravenous 106mg/kg (106mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Farmakologiya i Toksikologiya Vol. 27, Pg. 681, 1964.

Safety Profile

Safety Information of 5-Methoxytryptamine (CAS NO.608-07-1):
Hazard Codes:Xn
Risk Statements:22-36/37/38-20/21/22
22:Harmful if swallowed
36/37/38:Irritating to eyes, respiratory system and skin
20/21/22:Harmful by inhalation, in contact with skin and if swallowed
Safety Statements:36-26
36:Wear suitable protective clothing
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
WGK Germany:3
RTECS:NL4110000
F:8
Poison by intravenous and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Specification

First Aid Measures of 5-Methoxytryptamine (CAS NO.608-07-1):
Ingestion:If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation:If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin:In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes:In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Storage of 5-Methoxytryptamine (CAS NO.608-07-1):
Keep tightly closed.

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