- Ethyl (13-cis)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoate
- ethyl (1R,2R)-1-phenyl-2-(trideuteriomethylamino)cyclohex-3-ene-1-carboxylate,hydrochloride
- Ethyl (1S,2R)-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate hydrochloride
- Ethyl (2,4,6-trimethylbenzoyl) phenylphosphinate
- Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate
- Ethyl (2-bromopropionamido)acetate
- Ethyl (2-cyanoimino-5,6-dichloro-1,2,3,4-tetrahydroquinazolin-3-yl)acetate
- ETHYL (2E,4Z)-DECADIENOATE
- Ethyl (2-hydroxyethyl)dimethyl-ammonium benzilate chloride
- Ethyl (2-mercaptoethyl) carbamate S-ester with O,O-dimethyl phosphorodithioate
- 40463-09-03-Pentanone,4-methyl-1-phenyl-
- 40464-54-8Furan,heptafluorotetrahydro(1,1,2,2,3,3,4,4,4-nonafluorobutyl)-
- 40465-45-0Benzonitrile,4-isocyanato-
- 40465-66-5Glycine,N-(phosphonomethyl)-, ammonium salt (1:1)
- 40469-85-0(S)-Homo-beta-valine
- 40469-87-2Hexanoic acid, 3-amino-4-methyl-, (3S,4S)-
- 404-70-6Benzeneethanamine,3-fluoro-
- 40470-68-61,1'-Biphenyl,4,4'-bis[2-(2-methoxyphenyl)ethenyl]-
- 404-71-7Benzene,1-fluoro-3-isocyanato-
- 4047-24-9Ethanone,1-[2-hydroxy-6-(phenylmethoxy)- phenyl]-
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Ethyl 4'-hydroxy-3'-methoxycinnamate |
EINECS | 223-745-5 |
| CAS No. | 4046-02-0 | Density | 1.173 g/cm3 |
| PSA | 55.76000 | LogP | 1.97710 |
| Solubility | N/A | Melting Point |
63-65 °C(lit.) |
| Formula | C12H14O4 | Boiling Point | 382.3 °C at 760 mmHg |
| Molecular Weight | 222.241 | Flash Point | 132.5 °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | 26-37/39-36 | Risk Codes | 36/37/38 |
| Molecular Structure |
|
Hazard Symbols |
 Xi
|
| Synonyms |
Ethyl ferulate;2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, ethyl ester;UNII-5B8915UELW;AI3-23714; |
Article Data | 90 |
Ethyl 4'-hydroxy-3'-methoxycinnamate Synthetic route
- 1135-24-6
(E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid
- 64-17-5
ethanol
- 4046-02-0
ethyl 4-hydroxy-3-methoxycinnamate
| Conditions | Yield |
|---|---|
| With acetyl chloride at 20℃; | 100% |
| With sulfuric acid at 88℃; under 1034.32 Torr; for 0.05h; Microwave irradiation; | 94% |
| With sulfuric acid for 4h; Reflux; | 94% |
| Conditions | Yield |
|---|---|
| Stage #1: hydrogen ethyl malonate; vanillin With piperidine; pyridine at 100℃; for 24h; Knoevenagel Condensation; Stage #2: With hydrogenchloride In water at -10 - 0℃; for 24h; | 98% |
| With piperidine In pyridine at 100℃; for 8h; Knoevenagel Condensation; | 97% |
| With piperidine; pyridine; aniline | |
| With pyridine Knoevenagel Condensation; Reflux; |
- 6635-27-4
ethyl (E)-3-(4-acetoxy-3-methoxyphenyl)-prop-2-enoate
- 4046-02-0
ethyl 4-hydroxy-3-methoxycinnamate
| Conditions | Yield |
|---|---|
| With ammonium acetate In methanol at 20℃; for 3.5h; | 98% |
| With silica-supported phosphomolybdic acid In methanol at 20℃; for 2h; | 96% |
- 1135-24-6
3-(4-hydroxy-3-methoxyphenyl)acrylic acid
- 64-17-5
ethanol
- 4046-02-0
ethyl 4-hydroxy-3-methoxycinnamate
| Conditions | Yield |
|---|---|
| With sulfuric acid for 12h; | 96% |
| With sulfuric acid Reflux; | 92% |
| With acetyl chloride at 0 - 20℃; Inert atmosphere; | 86% |
| With sulfuric acid Fischer-Speier Esterification; Sealed tube; Heating; Microwave irradiation; |
- 121-33-5
vanillin
- 1099-45-2
ethyl (triphenylphosphoranylidene)acetate
- 4046-02-0
ethyl 4-hydroxy-3-methoxycinnamate
| Conditions | Yield |
|---|---|
| In toluene for 4h; Wittig Olefination; Reflux; | 95% |
| In chloroform Reflux; | 85% |
| In chloroform for 5h; Wittig Olefination; Inert atmosphere; Reflux; | 85% |
| Conditions | Yield |
|---|---|
| With Hoveyda-Grubbs catalyst first generation In 1,2-dichloro-ethane at 70℃; Cross Metathesis; Schlenk technique; Inert atmosphere; Glovebox; | 95% |
- 4046-02-0
ethyl 4-hydroxy-3-methoxycinnamate
| Conditions | Yield |
|---|---|
| bismuth(lll) trifluoromethanesulfonate In tetrahydrofuran; water at 20℃; for 0.166667h; | 92% |
- 64-17-5
ethanol
- 138769-50-3, 108608-04-4
trans-4-hydroxy-3-methoxycinnamic acid chloride
- 4046-02-0
ethyl 4-hydroxy-3-methoxycinnamate
| Conditions | Yield |
|---|---|
| With pyridine; potassium carbonate In dichloromethane; chloroform; toluene at 70℃; for 6h; Temperature; Reagent/catalyst; | 87.8% |
| With pyridine; potassium carbonate; triethylamine In dichloromethane; chloroform; toluene at 70℃; for 6h; Solvent; Reagent/catalyst; Concentration; Temperature; Time; | 87.8% |
- 1530-45-6
(carbethoxymethyl)triphenylphosphonium bromide
- 121-33-5
vanillin
- 4046-02-0
ethyl 4-hydroxy-3-methoxycinnamate
| Conditions | Yield |
|---|---|
| With Amberlite IR-400 In N,N-dimethyl-formamide at 95℃; for 10h; Inert atmosphere; | 80% |
- 121-33-5
vanillin
- 1099-45-2
ethyl (triphenylphosphoranylidene)acetate
A
- 4046-02-0
ethyl 4-hydroxy-3-methoxycinnamate
- 4046-02-0, 28028-62-8, 74257-26-4
cis-3-(4-Hydroxy-3-methoxyphenyl)-2-propensaeure-ethylester
| Conditions | Yield |
|---|---|
| In dichloromethane at 50℃; under 10000 Torr; for 12h; Product distribution; other solvent, time, pressure, other sibstituent. aldehydes; | |
| In dichloromethane at 50℃; under 10000 Torr; for 12h; Yield given. Yields of byproduct given; | |
| In dichloromethane at 50℃; for 12h; normal pressure; Yield given. Yields of byproduct given; |
Ethyl 4'-hydroxy-3'-methoxycinnamate Chemical Properties
Molecular structure of Ethyl ferulate (CAS NO.4046-02-0) is:
Product Name: Ethyl ferulate
CAS Registry Number: 4046-02-0
IUPAC Name: ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
Molecular Weight: 222.23716 [g/mol]
Molecular Formula: C12H14O4
XLogP3: 2.2
H-Bond Donor: 1
H-Bond Acceptor: 4
EINECS: 223-745-5
Melting Point: 63-65 °C(lit.)
Surface Tension: 43.4 dyne/cm
Sensitive: Light Sensitive
Density: 1.173 g/cm3
Flash Point: 132.5 °C
Enthalpy of Vaporization: 65.54 kJ/mol
Boiling Point: 382.3 °C at 760 mmHg
Vapour Pressure: 2.17E-06 mmHg at 25°C
Product Categories: Aromatic Esters; Cinnamic acid
Ethyl 4'-hydroxy-3'-methoxycinnamate Safety Profile
Safty information about Ethyl ferulate (CAS NO.4046-02-0) is:
Hazard Codes: 
Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-37/39-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39:Wear suitable gloves and eye/face protection.
S36:Wear suitable protective clothing.
WGK Germany: 3
Hazard Note: Irritant
Ethyl 4'-hydroxy-3'-methoxycinnamate Specification
Ethyl ferulate , its cas register number is 4046-02-0. It also can be called AI3-23714 ; UNII-5B8915UELW ; 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, ethyl ester ; Ethyl 4'-hydroxy-3'-methoxycinnamate .
What can I do for you?
Get Best Price
