Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Ethyl2-(2-methoxyphenoxy)acetate

Related Products

Hot Products

Name

Ethyl2-(2-methoxyphenoxy)acetate

EINECS 235-977-4
CAS No. 13078-21-2 Density 1.103 g/cm3
PSA 44.76000 LogP 1.63710
Solubility N/A Melting Point N/A
Formula C11H14O4 Boiling Point 278.7 °C at 760 mmHg
Molecular Weight 210.23 Flash Point 118 °C
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 13078-21-2 (ETHYL 2-METHOXYPHENOXYACETATE) Hazard Symbols N/A
Synonyms

Aceticacid, (2-methoxyphenoxy)-, ethyl ester (9CI);Acetic acid, (o-methoxyphenoxy)-,ethyl ester (6CI,7CI,8CI);Ethyl 2-(2-methoxyphenoxy)acetate;Ethyl (2-methoxyphenoxy)acetate;AC1L34QH;AC1Q65CB;CID83114;

Article Data 33

Ethyl2-(2-methoxyphenoxy)acetate Synthetic route

105-36-2

ethyl bromoacetate

90-05-1

2-methoxy-phenol

13078-21-2

ethyl 2-(2-methoxyphenoxy)acetate

Conditions
ConditionsYield
With potassium carbonate In acetone Reflux;99%
Stage #1: 2-methoxy-phenol With potassium carbonate In acetone at 20℃; for 0.25h; Inert atmosphere;
Stage #2: ethyl bromoacetate In acetone at 0℃; for 8h; Inert atmosphere; Reflux;
90%
Stage #1: 2-methoxy-phenol With potassium carbonate In acetone at 20℃; for 0.25h;
Stage #2: ethyl bromoacetate In acetone at 20 - 65℃;
90%
64-17-5

ethanol

1878-85-9

(2-methoxyphenoxy)acetic acid

13078-21-2

ethyl 2-(2-methoxyphenoxy)acetate

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 20℃;92%
With toluene-4-sulfonic acid for 5h; Heating;
105-39-5

chloroacetic acid ethyl ester

90-05-1

2-methoxy-phenol

13078-21-2

ethyl 2-(2-methoxyphenoxy)acetate

Conditions
ConditionsYield
With ethanol; sodium
With potassium carbonate; potassium iodide In acetone
With potassium carbonate In acetone for 15h; Heating;
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

13078-21-2

ethyl 2-(2-methoxyphenoxy)acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium formate / water / 15 h / 110 °C
2: potassium carbonate / acetonitrile
View Scheme
Multi-step reaction with 3 steps
1: water / 15 h / 110 °C
2: zinc; formic acid / water / 7 h / 110 °C / Sealed tube
3: potassium carbonate / acetonitrile
View Scheme
Multi-step reaction with 3 steps
1: zinc / water / 7 h / 100 °C / Sealed tube
2: zinc; formic acid / water / 7 h / 110 °C / Sealed tube
3: potassium carbonate / acetonitrile
View Scheme

C19H20O7

13078-21-2

ethyl 2-(2-methoxyphenoxy)acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: zinc; formic acid / water / 7 h / 110 °C / Sealed tube
2: potassium carbonate / acetonitrile
View Scheme
56122-34-0

1-(4-hydroxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol

13078-21-2

ethyl 2-(2-methoxyphenoxy)acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: formic acid; sodium formate / water / 110 °C
2: potassium carbonate / acetonitrile
View Scheme

2-(2-methoxyphenoxy)-1-phenylethan-1-ol

13078-21-2

ethyl 2-(2-methoxyphenoxy)acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: nano-Pd1Ni4 /MIL-100(Fe) / water / 6 h / 130 °C / Inert atmosphere
2.1: potassium carbonate / acetone / 0.25 h / 20 °C
2.2: 20 - 65 °C
View Scheme
14385-48-9

2-(2-methoxyphenoxy)-acetophenone

13078-21-2

ethyl 2-(2-methoxyphenoxy)acetate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium tetrahydroborate / methanol / 4 h / 25 °C
2.1: nano-Pd1Ni4 /MIL-100(Fe) / water / 6 h / 130 °C / Inert atmosphere
3.1: potassium carbonate / acetone / 0.25 h / 20 °C
3.2: 20 - 65 °C
View Scheme

1-(3-methoxylphenyl)-2-(2-methoxyphenoxy)ethanone

13078-21-2

ethyl 2-(2-methoxyphenoxy)acetate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium tetrahydroborate / methanol / 4 h / 25 °C
2.1: nano-Pd1Ni4 /MIL-100(Fe) / water / 6 h / 150 °C / Inert atmosphere
3.1: potassium carbonate / acetone / 0.25 h / 20 °C
3.2: 20 - 65 °C
View Scheme
19513-80-5

2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)ethan-1-one

13078-21-2

ethyl 2-(2-methoxyphenoxy)acetate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium tetrahydroborate / methanol / 4 h / 25 °C
2.1: nano-Pd1Ni4 /MIL-100(Fe) / water / 6 h / 150 °C / Inert atmosphere
3.1: potassium carbonate / acetone / 0.25 h / 20 °C
3.2: 20 - 65 °C
View Scheme

Ethyl2-(2-methoxyphenoxy)acetate Specification

The Acetic acid,2-(2-methoxyphenoxy)-, ethyl ester with CAS registry number of 13078-21-2 is also known as Ethyl (2-methoxyphenoxy)acetate. The IUPAC name is Ethyl 2-(2-methoxyphenoxy)acetate. Its EINECS registry number is 235-977-4. In addition, the formula is C11H14O4 and the molecular weight is 210.23.

Physical properties about Acetic acid,2-(2-methoxyphenoxy)-, ethyl ester are: (1)ACD/LogP: 1.76; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.76; (4)ACD/LogD (pH 7.4): 1.76; (5)ACD/BCF (pH 5.5): 12.86; (6)ACD/BCF (pH 7.4): 12.86; (7)ACD/KOC (pH 5.5): 216.55; (8)ACD/KOC (pH 7.4): 216.55; (9)#H bond acceptors: 4; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 6; (12)Polar Surface Area: 44.76Å2; (13)Index of Refraction: 1.492; (14)Molar Refractivity: 55.28 cm3; (15)Molar Volume: 190.4 cm3; (16)Polarizability: 21.91×10-24cm3; (17)Surface Tension: 35.4 dyne/cm; (18)Density: 1.103 g/cm3; (19)Flash Point: 118 °C; (20)Enthalpy of Vaporization: 51.74 kJ/mol; (21)Boiling Point: 278.7 °C at 760 mmHg; (22)Vapour Pressure: 0.00419 mmHg at 25 °C.

Uses of Acetic acid,2-(2-methoxyphenoxy)-, ethyl ester: it is used to produce (2-Methoxy-phenoxy)-acetic acid hydrazide. The reaction occurs with reagent Hydrazine hydrate and solvent Ethanol. Besides, the reaction needs other condition of heating for 12 hours. The yield is 65%.

Acetic acid, 2-(2-methoxyphenoxy)-, ethyl ester is used to produce (2-Methoxy-phenoxy)-acetic acid hydrazide.

You can still convert the following datas into molecular structure:
1. SMILES: O=C(OCC)COc1ccccc1OC
2. InChI: InChI=1/C11H14O4/c1-3-14-11(12)8-15-10-7-5-4-6-9(10)13-2/h4-7H,3,8H2,1-2H3
3. InChIKey: BZCGGCRVJFWCIW-UHFFFAOYAV
4. Std. InChI: InChI=1S/C11H14O4/c1-3-14-11(12)8-15-10-7-5-4-6-9(10)13-2/h4-7H,3,8H2,1-2H3
5. Std. InChIKey: BZCGGCRVJFWCIW-UHFFFAOYSA-N

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 13078-21-2