Welcome to LookChem.com Sign In | Join Free Post buying lead Chemical Tools
Home > Hot Product_List > Ketorolac

Basic information

  • Name:
  • Ketorolac

  • CAS No.:
  • 74103-06-3

  • Molecular Structure:
  • Formula:
  • C15H13NO3
  • Molecular Weight:
  • 255.27
  • Deleted CAS:
  • 66635-83-4
  • Synonyms:
  • 1H-Pyrrolizine-1-carboxylicacid, 5-benzoyl-2,3-dihydro-, (?à)-;1H-Pyrrolizine-1-carboxylicacid, 5-benzoyl-2,3-dihydro-;(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;(+-)-Ketorolac;
  • Density:
  • 1.398 g/cm3
  • Melting Point:
  • 160-161 ºC
  • Boiling Point:
  • 223.7 ºC at 760 mmHg
  • Flash Point:
  • 89.1 ºC
  • Appearance:
  • white crystalline or white powder

Famous Chemical Enterprises

  • Livzon
  • Total
  • Shell
  • Dupont
  • Exxonmobil
  • Akzonobel
  • Basf
  • Bayer
  • BP

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Chemistry


IUPAC Name: 5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
Molecular Formula: C15H13NO3
Molecular Weight: 255.27 g/mol
SMILES: n12c([C@@H](C(O)=O)CC2)ccc1C(c1ccccc1)=O
InChI: InChI=1/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19)
Classification Code: Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Cyclooxygenase Inhibitors; Drug / Therapeutic Agent; Enzyme Inhibitors; Peripheral Nervous System Agents; Sensory System Agents
Product Categories: API's
Index of Refraction: 1.436 
Molar Refractivity: 30.52 cm
Molar Volume: 116.6 cm3 
Polarizability: 12.1×10-24 cm3 
Surface Tension: 28.4 dyne/cm 
Density: 1.398 g/cm3 
Flash Point: 89.1 °C 
Enthalpy of Vaporization: 46.02 kJ/mol 
Boiling Point: 223.7 °C at 760 mmHg 
Melting Point: 160-161 °C
Vapour Pressure of Ketorolac (CAS NO.74103-06-3): 0.0947 mmHg at 25 °C

Uses

 Ketorolac (CAS NO.74103-06-3) is a non-steroidal anti-inflammatory drug, often used as an analgesic, antipyretic (fever reducer), and anti-inflammatory. An ophthalmic (i.e., eye-drop) solution of Ketorolac is available and is used to treat eye pain and to relieve the itchiness and burning of seasonal allergies.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 200mg/kg (200mg/kg)   Agents and Actions, A Swiss Journal of Pharmacology. Vol. 12, Pg. 684, 1982.
mouse LDLo intraperitoneal 100mg/kg (100mg/kg)   Agents and Actions, A Swiss Journal of Pharmacology. Vol. 12, Pg. 684, 1982.
 

Safety Profile

RIDADR: 3249
HazardClass: 6.1(a)
PackingGroup of Ketorolac (CAS NO.74103-06-3): II

Specification

 Ketorolac (CAS NO.74103-06-3), its Synonyms are (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid ; (+-)-Ketorolac ; Ketorolacum ; 1H-Pyrrolizine-1-carboxylic acid, 2,3-dihydro-5-benzoyl-, (+-)- .

Please post your buying leads
so that our qualified suppliers will soon contact you!

©2008 LookChem.com,License:ICP NO.:Zhejiang10014259

[Hangzhou]86-571-85317600,85317603,85317620