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Name |
Methanesulfonic acid,hydrazide |
EINECS | -0 |
CAS No. | 10393-86-9 | Density | 1.401 g/cm3 |
PSA | 80.57000 | LogP | 0.58130 |
Solubility | N/A | Melting Point |
46-48 °C |
Formula | CH6N2O2S | Boiling Point | 229 °C at 760 mmHg |
Molecular Weight | 110.137 | Flash Point | 92.3 °C |
Transport Information | N/A | Appearance | N/A |
Safety | 15-26-36 | Risk Codes | 36/37/38 |
Molecular Structure | Hazard Symbols | R36/37/38:Irritating to eyes, respiratory system and skin.; | |
Synonyms |
Mesyl hydrazide; |
Article Data | 16 |
methanesulfonyl chloride
methanesulphonyl hydrazide
Conditions | Yield |
---|---|
With sodium hydroxide; hydrazine hydrate In water at 8℃; | 90% |
With hydrazine hydrate In tetrahydrofuran at 10 - 15℃; for 0.5h; | 82% |
With hydrazine hydrate In ethanol at 10 - 20℃; for 1h; | 50% |
methanesulfonyl chloride
A
methanesulphonyl hydrazide
B
di-methanesulfonyl hydrazide
Conditions | Yield |
---|---|
With sodium hydroxide; hydrazine hydrate In water cooling; |
1-phenyl-3-dimethylaminoprop-2-enone
methanesulphonyl hydrazide
2-methylsulfonyl-1-phenylethanone
Conditions | Yield |
---|---|
Stage #1: 1-phenyl-3-dimethylaminoprop-2-enone; methanesulphonyl hydrazide With tert.-butylhydroperoxide In water at 80℃; for 8h; Stage #2: With copper diacetate In water | 96% |
Conditions | Yield |
---|---|
In ethanol at 70℃; for 0.5h; Condensation; | 95% |
Conditions | Yield |
---|---|
With tert.-butylhydroperoxide; iodine; sodium carbonate In toluene at 90℃; for 3h; Inert atmosphere; stereoselective reaction; | 95% |
With oxygen; copper(l) chloride; lithium bromide In dimethyl sulfoxide at 100℃; under 760.051 Torr; for 12h; Schlenk technique; stereoselective reaction; | 88% |
Conditions | Yield |
---|---|
With tert.-butylhydroperoxide; iodine In water; 1,2-dichloro-ethane at 20℃; for 2h; Green chemistry; | 92% |
methanesulphonyl hydrazide
dimethoxyacetaldehyde
A
(E)-N'-(2,2-dimethoxyethylidene)methanesulfonohydrazide
Conditions | Yield |
---|---|
In tetrahydrofuran at 20℃; for 3.5h; | A 91.1% B n/a |
benzophenone
methanesulphonyl hydrazide
N'-(diphenylmethylene)methanesulfonohydrazide
Conditions | Yield |
---|---|
With hydrogenchloride In methanol; water for 24h; Reflux; | 90% |
With hydrogenchloride In methanol; water for 1h; Reflux; |
Conditions | Yield |
---|---|
With palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 20℃; for 24h; | 90% |
methanesulphonyl hydrazide
(3R,3aS,4R,SR,7S,9R,9aR,12R)-3-methoxy-4,7,9,12-tetramethyl-8-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl carbonochloridate
(3R)-3-deoxo-11-deoxy-3-methoxy-11-oxo-4-epi-mutilin 14-[N-(methanesulphonylamino) carbamate]
Conditions | Yield |
---|---|
In dichloromethane | 89% |
The Methanesulfonic acid,hydrazide, with the CAS registry number of 10393-86-9, is also known as Mesyl hydrazide. Its molecular formula is CH6N2O2S and molecular weight is 110.14. What's more, its IUPAC name is Methanesulfonohydrazide. In addition, it must be stored in airtight containers and placed in a dry, cool place.
Physical properties about the Methanesulfonic acid,hydrazide are: (1)ACD/LogP: -1.47; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 4; (4)#H bond donors: 3; (5)#Freely Rotating Bonds: 1; (6)Polar Surface Area: 49 Å2; (7)Index of Refraction: 1.491; (8)Molar Refractivity: 22.76 cm3; (9)Molar Volume: 78.5 cm3; (10)Surface Tension: 53.1 dyne/cm; (11)Density: 1.401 g/cm3; (12)Flash Point: 92.3 °C; (13)Enthalpy of Vaporization: 46.56 kJ/mol; (14)Boiling Point: 229 °C at 760 mmHg; (15)Vapour Pressure: 0.0711 mmHg at 25 °C.
Preparation: this chemical can be obtained by Methanesulfonyl chloride. The reaction needs reagent Hydrazine hydrate and solvent H2O. The reaction temperature is 8 °C. The yield is about 90 %.
Uses: it is used to produce other chemicals. For example, it is used to produce Phenyl methaneselenesulfonate. This reaction needs solvent CH2Cl2. The reaction time is 30 min. The yield is about 65 %.
When you are using this chemical, please be cautious about it as the following:
As a chemical, it is irritating to eyes, respiratory system and skin. If contact with eyes accidently, rinse immediately with plenty of water and seek medical advice. In addition, during using it, wear suitable protective clothing.
You can still convert the following datas into molecular structure:
(1) SMILES: O=S(=O)(NN)C
(2) InChI: InChI=1/CH6N2O2S/c1-6(4,5)3-2/h3H,2H2,1H3
(3) InChIKey: VKHZYWVEBNIRLX-UHFFFAOYAS