Basic information
- Name:
N-Acetyl-L-leucine
- CAS No.:
1188-21-2
- Molecular Structure:

- Formula:
- C8H15NO3
- Molecular Weight:
- 173.21
- Deleted CAS:
- 24160-46-1|90243-88-2
- Synonyms:
- Leucine,N-acetyl-, L- (8CI);(S)-2-Acetamido-4-methylpentanoic acid;Acetyl-L-leucine;Acetylleucine;N-Acetyl-L-(-)-leucine;
- EINECS:
- 214-706-3
- Density:
- 1.069 g/cm3
- Melting Point:
- 187-190 °C(lit.)
- Boiling Point:
- 369.7 °C at 760mmHg
- Flash Point:
- 177.4 °C
- Solubility:
- 0.81 g/100 mL (20 °C) in water
- Appearance:
- white crystalline powder
- Hazard Symbols:
Xi- Risk Codes:
- 36/37/38
- Safety Description:
- 24/25-36-26 Details
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Chemistry
Molecular structure of N-Acetyl-L-leucine (CAS NO.1188-21-2) is:

Product Name: N-Acetyl-L-leucine
CAS Registry Number: 1188-21-2
IUPAC Name: (2S)-2-acetamido-4-methylpentanoic acid
Molecular Weight: 173.2096 [g/mol]
Molecular Formula: C8H15NO3
XLogP3: 0.5
H-Bond Donor: 2
H-Bond Acceptor: 3
EINECS: 214-706-3
Melting Point: 187-190 °C(lit.)
Surface Tension: 37.2 dyne/cm
Water Solubility: 0.81 g/100 mL (20 °C)
Density: 1.069 g/cm3
Flash Point: 177.4 °C
Enthalpy of Vaporization: 67.7 kJ/mol
Boiling Point: 369.7 °C at 760 mmHg
Vapour Pressure: 1.77E-06 mmHg at 25°C
Product Categories: Amino Acids Derivatives;Amino Acid Derivatives;Amino Acids;Leucine [Leu, L];Amino Acids and Derivatives;Ac-Amino Acids;Amino Acids (N-Protected);Biochemistry;N-Acetyl-Amino acid series;Amino Acid Derivatives;Leucine;Peptide Synthesis
Uses
N-Acetyl-L-leucine (CAS NO.1188-21-2) is used for treating vestibular-related imbalance and vertigo.
Safety Profile
Safty information about N-Acetyl-L-leucine (CAS NO.1188-21-2) is:
Hazard Codes:
Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-26
S24/25:Avoid contact with skin and eyes.
S36:Wear suitable protective clothing.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
HazardClass: IRRITANT
Specification
N-Acetyl-L-leucine , its cas register number is 1188-21-2. It also can be called Acetylleucine ; Acetyl-L-leucine ; Acetylleucine ; L-Leucine, N-acetyl- ; Leucine, N-acetyl-, L- (8CI) ; N-Acetylleucine .It is a white crystalline powder.

