Reference

Metabolism of amino acids in Ascaridia galli: transamination

Metabolism of amino acids in Ascaridia galli: transamination. Singh, Govind; Srivastava, V. M.In this study， 61-90-5 and 63-68-3 are also used. L. (Div. Biochem., Cent. Drug Res. Inst., Lucknow 226001, India). Z. Parasitenkd., 69(6), 783-8 (English) 1983. CODEN: ZEPAA6. ISSN: 0044-3255. DOCUMENT TYPE: Journal CA Section: 12 (Nonmammalian Biochemistry) A. galli, Using 2-oxoglutaric acid as an acceptor, transaminates alanine and aspartic acid at high rates. Among other amino acids valine, phenylalanine, leucine, isoleucine, arginine, tyrosine, and methionine are metabolized at moderate rates, whereas lysine, serine, threonine, cysteine, glycine, histidine, tryptophan, DOPA, and GABA appear to be inert in this respect. Body parts mimic the whole worm in the pattern of transamination of various amino acids with the exception of methionine. Alanine, aspartic acid, and glutamic acid may transfer their amino groups also to pyruvate and oxalacetate. Alanine and aspartate transaminases are located mainly in the cytosol and mitochondrial fractions. .

In vitro degradation of leucine in muscle, adipose tissue, liver, and kidney of fed and starved sheep

In vitro degradation of leucine in muscle, adipose tissue, liver, and kidney of fed and starved sheep. Wijayasinghe, M. S.; Milligan, L. P.; Thompson, J. R. (Dep. Anim. Sci., Univ. Alberta, Edmonton, AB T6G 2P5, Can.). Biosci.Several substances with their cas registry numbers 816-66-0 and 61-90-5 may be metioned in this study. Rep., 3(12), 1133-40 (English) 1983. CODEN: BRPTDT. ISSN: 0144-8463. DOCUMENT TYPE: Journal CA Section: 13 (Mammalian Biochemistry) Section cross-reference(s): 18 In vitro rates of conversion of [1-14C]leucine to 4-methyl-2-oxo[1-14C]pentanoate and of oxidn. of [1-14C]- and [U-14C]leucine were measured for muscle, adipose tissue, liver, and kidneys from fed and starved (5 days) sheep. Skeletal muscle was likely the major site of leucine catabolism in sheep although adipose tissue was capable of substantial metab. Muscle and adipose tissue from fed sheep released 17 and 5% of the [1-14C]leucine transaminated as 4-methyl-2-oxo-[1-14C]pentanoate, and on starvation the proportions were increased to 46 and 32%, resp. Starvation reduced leucine catabolism in all tissues except the kidney. The pattern of leucine catabolism in muscle changed from extensive oxidn. in the fed state to being limited essentially to transamination and decarboxylation in the starved state. .