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Basic information

  • Name:
  • Hydrazine,phenyl-, hydrochloride (1:1)

  • Superlist Name:
  • Phenylhydrazine hydrochloride
  • CAS No.:
  • 59-88-1

  • Molecular Structure:
  • Formula:
  • C6H8N2.HCl
  • Molecular Weight:
  • 144.61 .
  • Synonyms:
  • Hydrazine,phenyl-, monohydrochloride (8CI,9CI);N-Phenylhydrazine hydrochloride;Phenylhydrazine monohydrochloride;Phenylhydrazinium chloride;Phenylhydrazinehydrochloride;
  • EINECS:
  • 200-444-7
  • Melting Point:
  • 250-254 °C (dec.)(lit.)
  • Boiling Point:
  • 243 °C at 760 mmHg
  • Flash Point:
  • 115.4 °C
  • Appearance:
  • white to tan solid
  • Hazard Symbols:
  • ToxicT, DangerousN
  • Risk Codes:
  • 45-23/24/25-36/38-43-48/23/24/25-50-68
  • Safety Description:
  • 53-45-61 Details
  • Transport Information:
  • UN 2811 6.1/PG 3

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Consensus Reports

Reported in EPA TSCA Inventory. EPA Extremely Hazardous Substances List.

Standards and Recommendations

NIOSH REL: (Hydrazines) CL 0.6 mg/m3/2H

Specification

The Phenylhydrazine hydrochloride is an organic compound with the formula C6H8N2.HCl. The IUPAC name of this chemical is phenylhydrazine hydrochloride. With the CAS registry number 59-88-1, it is also named as Phenylhydrazinium Chloride. The product's categories are Hydrazines; Nitrogen Compounds; Organic Building Blocks; Food & Beverage; Reagents for Analysis of Carbohydrates; Reagents for Food Analysis; HydrazinesStains and Dyes; P; Stains & Dyes, A to. Besides, it is a white to tan solid, which should be stored in a closed cool and dry place. It is used as intermediates in medicine, pesticide and dye.

Physical properties about Phenylhydrazine hydrochloride are: (1)ACD/LogP: 1.25 ; (2)ACD/LogD (pH 5.5): 1.04; (3)ACD/LogD (pH 7.4): 1.25; (4)ACD/BCF (pH 5.5): 3.26; (5)ACD/BCF (pH 7.4): 5.21; (6)ACD/KOC (pH 5.5): 70.82; (7)ACD/KOC (pH 7.4): 113.16; (8)#H bond acceptors: 2; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 2; (11)Polar Surface Area: 6.48 Å2; (12)Flash Point: 115.4 °C; (13)Enthalpy of Vaporization: 48 kJ/mol; (14)Boiling Point: 243 °C at 760 mmHg; (15)Vapour Pressure: 0.0329 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
It is toxic by inhalation, in contact with skin and if swallowed. It may cause sensitisation by skin contact and may cause cancer. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, this chemical is danger of serious damage to health by prolonged exposure through inhalation, in contact with skin and if swallowed. It is very toxic to aquatic organisms. When you are using it, avoid release to the environment. Refer to special instructions/safety data sheet. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: Cl.NNc1ccccc1
(2)InChI: InChI=1/C6H8N2.ClH/c7-8-6-4-2-1-3-5-6;/h1-5,8H,7H2;1H CopyCopied
(3)InChIKey: JOVOSQBPPZZESK-UHFFFAOYAS
(4)Std. InChI: InChI=1S/C6H8N2.ClH/c7-8-6-4-2-1-3-5-6;/h1-5,8H,7H2;1H
(5)Std. InChIKey: JOVOSQBPPZZESK-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 900ug/kg (0.9mg/kg)   Quarterly Journal of Crude Drug Research. Vol. 9, Pg. 1455, 1969.
mouse LD50 oral 2100mg/kg (2100mg/kg)   Quarterly Journal of Crude Drug Research. Vol. 9, Pg. 1455, 1969.
mouse LD50 subcutaneous 89mg/kg (89mg/kg)   Farmaco, Edizione Scientifica. Vol. 9, Pg. 274, 1954.
rabbit LDLo oral 25mg/kg (25mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rabbit LDLo skin 500mg/kg (500mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

SKIN AND APPENDAGES (SKIN): CORROSIVE: AFTER TOPICAL EXPOSURE
Fundamental and Applied Toxicology. Vol. 8, Pg. 583, 1987.
rabbit LDLo subcutaneous 25mg/kg (25mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rat LD50 intraperitoneal 161mg/kg (161mg/kg)   Acta Biologica et Medica Germanica. Vol. 18, Pg. 617, 1967.

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