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15086-94-9

Basic Information
CAS No.: 15086-94-9
Name: Solvent Red 43
Article Data: 16
Molecular Structure:
Molecular Structure of 15086-94-9 (Solvent Red 43)
Formula: C20H8Br4O5
Molecular Weight: 647.897
Synonyms: Fluorescein,2',4',5',7'-tetrabromo- (7CI,8CI);3,6-Dihydroxy-2,4,5,7-tetrabromospiro[xanthene-9,3'-phthalide];C.I. 45380:2;C.I. Solvent Red 43;D and C Red No. 21;C Red No. 21;Eosin Y spirit soluble;Eosin acid;Eosine acid;Japan Red 223;
EINECS: 239-138-3
Density: 1.02 g/mL at 20oC
Melting Point: 300 °C
Boiling Point: 640.3 °C at 760 mmHg
Flash Point: 341 °C
Appearance: orange-brown powder
Hazard Symbols: IrritantXi
Risk Codes: 36
Safety: 26
Transport Information: UN 1170 3/PG 2
PSA: 93.40000
LogP: 6.12210
Synthetic route
2321-07-5

fluorescein

15086-94-9

eosin y

Conditions
ConditionsYield
With Oxone; sodium bromide at 200℃; for 12h;100%
With sodium hypochlorite; hydrogen bromide; sodium sulfite In 2-methyltetrahydrofuran; water at 20℃; for 3h; Flow reactor;78%
With ethanol; bromine
518-47-8

fluorescein disodium salt

15086-94-9

eosin y

Conditions
ConditionsYield
With N-Bromosuccinimide In ethanol at 20℃; for 0.5h;89%
85-44-9

phthalic anhydride

18011-67-1

2,4-dibromo-1,3-benzenediol

15086-94-9

eosin y

Conditions
ConditionsYield
With zinc(II) chloride
3341-06-8

3,5-dibromo-2'-carboxy-2,4-dihydroxybenzophenone

5435-44-9, 22243-66-9

(E)-3-Ureido-but-2-enoic acid ethyl ester

A

85-44-9

phthalic anhydride

B

15086-94-9

eosin y

Conditions
ConditionsYield
at 230 - 240℃;
3341-06-8

3,5-dibromo-2'-carboxy-2,4-dihydroxybenzophenone

A

85-44-9

phthalic anhydride

B

15086-94-9

eosin y

Conditions
ConditionsYield
With zinc(II) chloride at 235 - 240℃; im Wasserstoffstrom;
596-28-1

3,3-bis-(3,4-dihydroxy-phenyl)-3H-isobenzofuran-1-one

3147-46-4

3,5-dibromo-4-hydroxysalicylic acid

5435-44-9, 22243-66-9

(E)-3-Ureido-but-2-enoic acid ethyl ester

15086-94-9

eosin y

Conditions
ConditionsYield
at 170℃;
152-75-0

eosine

15086-94-9

eosin y

Conditions
ConditionsYield
In 1,4-dioxane Equilibrium constant; Investigation of the effect of various organic solvents.;
518-47-8

fluorescein sodium salt

15086-94-9

eosin y

Conditions
ConditionsYield
With potassium bromate; sulfuric acid; potassium bromide In water; acetone for 2h;1.15 g
7664-93-9

sulfuric acid

26799-78-0

Eosin ethyl ester

15086-94-9

eosin y

Conditions
ConditionsYield
at 150℃;
64-17-5

ethanol

2321-07-5

fluorescein

bromine (4 mol)

bromine (4 mol)

15086-94-9

eosin y

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Chemistry

Molecular Structure of BROMEOSIN(15086-94-9):

IUPAC Name:2',4',5',7'-tetrabromo-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
Molecular Formula:C20H8Br4O5
Molecular Weight:647.890520 g/mol
Appearance:red-brown crystalline powder
Melting Point:300 °C
Density:2.5 g/cm3
Flash Point:341 °C
Enthalpy of Vaporization:97.98 kJ/mol
Boiling Point:640.3 °C at 760 mmHg
Vapour Pressure:5.42E-17 mmHg at 25 °C
EINECS:241-409-6
Synonyms of BROMEOSIN(15086-94-9):
BROMO ACID J;BROMO ACID J TS, XL, OR XX;BROMOFLUORESCEIN;BRONZE BROMO ES;EOSIN Y;EOSIN Y DISODIUM SALT;EOSIN YELLOWISH WATER-SOLUBLE;EOSIN YELLOWISH Y;Solvent Red 43
Categories of BROMEOSIN(15086-94-9):Organics

Uses

BROMEOSIN(15086-94-9) is used as a biological stain.

Toxicity Data With Reference

1.   

dnr-bcs 2 mg/disc

   TRENAF    Kenkyu Nenpo-Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. 27 (1976),153.
2.   

scu-mus LDLo:450 mg/kg

   HBAMAK    “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1289.
3.   

scu-frg LDLo:1 g/kg

   HBAMAK    “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1289.

Consensus Reports

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) , Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 (1977),p. 183(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory.

Safety Profile

The safety information of BROMEOSIN(15086-94-9) is as follows:
Hazard Codes:Xi
Risk Statements:36
36:Irritating to the eyes
Safety Statements:26
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
RIDADR:UN 1170 3/PG 2
WGK Germany:3
RTECS:LM5850000
Mutation data reported. Incompatible with reducing agents. When heated to decomposition it emits very toxic fumes of Br. See also BROMIDES.

Specification

Storage information of BROMEOSIN(15086-94-9):
Store in a cool, dry place. Store in a tightly closed container.