Products Categories
CAS No.: | 2577-90-4 |
---|---|
Name: | methyl 3-phenyl-L-alaninate |
Article Data: | 198 |
Molecular Structure: | |
Formula: | C10H13NO2 |
Molecular Weight: | 179.219 |
Synonyms: | Methyl 3-phenyl-L-alaninate; |
EINECS: | 219-934-7 |
Density: | 1.1 g/cm3 |
Melting Point: | 131-133 °C |
Boiling Point: | 264.2 °C at 760 mmHg |
Flash Point: | 126 °C |
PSA: | 52.32000 |
LogP: | 1.42970 |
Conditions | Yield |
---|---|
With thionyl chloride | 100% |
With thionyl chloride at -10 - 20℃; Inert atmosphere; | 100% |
With thionyl chloride at 0 - 20℃; | 99% |
methyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-phenylalaninate
phenylmethanethiol
A
methyl (2S)-2-amino-3-phenylpropanoate
Conditions | Yield |
---|---|
With tetrabutyl ammonium fluoride In N,N-dimethyl-formamide for 0.0333333h; Product distribution; other protected peptides, other thiol, var. TBAF conc., var. time, var. solvent, with or without ultrasound mixing; | A n/a B 100% |
With tetrabutyl ammonium fluoride In N,N-dimethyl-formamide for 0.05h; | A n/a B 100% |
(E)-α-(N-acylamino)cinnamic acid methyl ester
methyl (2S)-2-amino-3-phenylpropanoate
Conditions | Yield |
---|---|
With hydrogen; (S)Fc-α-S(C5H5)Fe(C5H3(PPh2)CH(OH)C6H4(PPh2)); [Rh(norbornadiene)2]BF4 In methanol at 25℃; under 750.075 Torr; for 1h; Product distribution / selectivity; | 100% |
With hydrogen; (S)-1-diphenylphosphino-2-[α-(S)-methoxy(o-diphenylphosphinophenyl)methyl]ferrocene; [Rh(norbornadiene)2]BF4 In methanol at 25℃; under 750.075 Torr; for 1h; Product distribution / selectivity; | 100% |
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
methyl (2S)-2-amino-3-phenylpropanoate
Conditions | Yield |
---|---|
With Amberlyst A21 In dichloromethane at 0 - 20℃; for 2h; stereoselective reaction; | 99% |
With Amberlyst A21 resin In dichloromethane at 0 - 20℃; for 2h; Reagent/catalyst; | 99% |
With potassium carbonate In dichloromethane; water at 20℃; | 97% |
N-carbobenzoxy-L-phenylalanine methyl ester
methyl (2S)-2-amino-3-phenylpropanoate
Conditions | Yield |
---|---|
With hydrogen In methanol at 27℃; under 750.075 Torr; for 2h; Reagent/catalyst; Green chemistry; | 99% |
methyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-phenylalaninate
methyl (2S)-2-amino-3-phenylpropanoate
Conditions | Yield |
---|---|
With piperazine; diethyl {[(1-methoxy-1-oxo-3-phenylpropan-2-yl)amino]methylidene}propanedioate In ethanol at 20℃; for 0.5h; | 98% |
With sodium azide In N,N-dimethyl-formamide at 50℃; for 3h; | 97% |
With triethylamine; 1-butyl-3-methylimidazolium Tetrafluoroborate In neat (no solvent) at 25℃; Green chemistry; | 82% |
With aluminium trichloride; N,N-dimethyl-aniline In dichloromethane for 4h; Heating; | |
With Octanethiol; tetrabutyl ammonium fluoride In N,N-dimethyl-formamide for 0.166667h; Inert atmosphere; |
N-Cbz-L-Asp
A
methyl (2S)-2-amino-3-phenylpropanoate
B
N-carbobenzyloxy-L-aspartyl-L-phenylalanine methyl ester
Conditions | Yield |
---|---|
In N-methyl-acetamide; water | A 95.5% B n/a |
Conditions | Yield |
---|---|
With sodium hydroxide; sulfuric acid In methanol; water | 94.5% |
N-(((tert-butyldimethylsilyl)oxy)carbonyl)phenylalanine methyl ester
methyl (2S)-2-amino-3-phenylpropanoate
Conditions | Yield |
---|---|
With tetrabutyl ammonium fluoride In tetrahydrofuran for 1h; Ambient temperature; | 93% |
(S)-2-(2-Aza-bicyclo[2.2.1]hept-5-en-2-yl)-3-phenyl-propionic acid methyl ester
methyl (2S)-2-amino-3-phenylpropanoate
Conditions | Yield |
---|---|
Bio-Rad AG 50W-X2 In ethanol at 45℃; for 1.5h; | 93% |
What can I do for you?
Get Best Price
The L-Phenylalanine, methylester, with the CAS registry number 2577-90-4, is also known as Methyl 3-phenyl-L-alaninate. Its EINECS registry number is 219-934-7. This chemical's molecular formula is C10H13NO2 and molecular weight is 179.21572. What's more, its systematic name is Methyl L-phenylalaninate.
Physical properties about L-Phenylalanine, methylester are: (1)ACD/LogP: 1.27; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 3; (4)#H bond donors: 2; (5)#Freely Rotating Bonds: 5; (6)Polar Surface Area: 29.54 Å2; (7)Index of Refraction: 1.53; (8)Molar Refractivity: 50.33 cm3; (9)Molar Volume: 162.8 cm3; (10)Polarizability: 19.95×10-24 cm3; (11)Surface Tension: 42 dyne/cm; (12)Density: 1.1 g/cm3; (13)Flash Point: 126 °C; (14)Enthalpy of Vaporization: 50.2 kJ/mol; (15)Boiling Point: 264.2 °C at 760 mmHg; (16)Vapour Pressure: 0.00986 mmHg at 25 °C.
Preparation of L-Phenylalanine, methylester: this chemical is prepared by reaction of L-Phenylalanine with Methanol by heating. The reaction needs reagent Thionyl chloride. The yield is about 95 %.
Uses of L-Phenylalanine, methylester: it is used to produce other chemicals. For example, it is used to produce L-Phenylalanine amide at ambient temperature. The reaction needs reagent aq. NH4OH and solvent Toluene. The reaction time is 16 hours. The yield is about 79 %.
You can still convert the following datas into molecular structure:
(1) SMILES: O=C(OC)[C@@H](N)Cc1ccccc1
(2) InChI: InChI=1/C10H13NO2/c1-13-10(12)9(11)7-8-5-3-2-4-6-8/h2-6,9H,7,11H2,1H3/t9-/m0/s1
(3) InChIKey: VSDUZFOSJDMAFZ-VIFPVBQEBN