Reference

Azetidine derivatives

Azetidine derivatives. Umezawa, Hamao; Oono, Masaji; Ishihama, Hiroshi; Kyotani, Yoshinori; Takahashi, Yoshio (Kowa Co., Ltd. , Japan). Eur. Pat. Appl. EP 91239 A1 12 Oct 1983, 39 pp. DESIGNATED STATES: R: DE, FR, GB, IT. (English). (European Patent Organization). CODEN: EPXXDW. CLASS: IC: C07F007-18. APPLICATION: EP 83-301648 24 Mar 1983.Several substances with their cas registry numbers 88986-87-2 and 88986-92-9 may be metioned in this study. PRIORITY: JP 82-47829 25 Mar 1982; JP 82-81195 14 May 1982. DOCUMENT TYPE: Patent CA Section: 29 (Organometallic and Organometalloidal Compounds) Section cross-reference(s): 26 About 5 different prepns. of I (R = H, OH; R1-R6 = lower alkyl) were described. Thus, 4S-4-(methoxycarbonylmethyl)azetidin-2-one was treated with Me3CSiMe2Cl at 0°, then reduced with LiAlH4, and treated with Me3CSiMe2Cl to give 4R-1-(tert-butyldimethylsilyl)-4-(2-tert-butyldimethylsiloxyethyl)azetidin-2- one. The latter was lithiated with BuLi in diisopropylamine at -78°, treated with Me3SiCl, then with 1-(methylthiomethyl)oxypropan-2-one to give I (R1, R4 = Me3C; R2, R3, R5, R6 = Me; R = OCH2SMe) (II). II was hydrolyzed in aq. MeCN contg. HgCl2 and CaCO3 to give I (same R1-R6; R = OH). Also prepd. was III. .

The gas-phase structure of azetidine: microwave spectroscopy, and electron diffraction and normal coordinate analysis

The gas-phase structure of azetidine: microwave spectroscopy, and electron diffraction and normal coordinate analysis. Guenther, Horst; Schrem, Gisela; Oberhammer, Heinz (Kernforschungszent. Karlsruhe, Karlsruhe 7500, Fed. Rep. Ger.). J. Mol. Spectrosc., 104(1), 152-64 (English) 1984. CODEN: JMOSA3. ISSN: 0022-2852. DOCUMENT TYPE: Journal CA Section: 73 (Optical, Electron, and Mass Spectroscopy and Other Related Properties) Section cross-reference(s): 22 The geometric structure of azetidine was detd. by a combined anal. of electron diffraction and microwave data, implementing the results of a normal coordinate anal. The following geometric parameters (rz values) for the ring skeleton were obtained: C-N = 1.473(3), C-C = 1.563(3) ?, CNC = 91.2(0.4)° and puckering angle q = 29.7(1.4)°. The microwave spectra were analyzed for the ground state of the parent and N-deuterated species and for the v = 1 and v = 2 states of the puckering vibration of the parent species. Dipole moments and N quadrupole consts. were detd.In this experiment, several chemicals are used like 503-29-7 and 24847-27-6 The structural parameters were compared to previous exptl. and theor. results for azetidine and are discussed in context with the isoelectronic cyclobutane and oxetane. .